Trifluoromethylation of aryl and heteroaryl halides

被引：286
作者：
Roy, Sudipta [1 ]
Gregg, Brian T. [1 ]
Gribble, Gordon W. [2 ]
Le, Van-Duc [1 ]
Roy, Sujata [1 ]
机构：
[1] AMRI, Dept Med Chem, 26 Corp Circle, Albany, NY 12212 USA
[2] Dartmouth Coll, Dept Chem, Hanover, NH 03755 USA
来源：
TETRAHEDRON | 2011年 / 67卷 / 12期
关键词：
CROSS-COUPLING REACTIONS; PHENYLETHANOLAMINE N-METHYLTRANSFERASE; FORMING REDUCTIVE ELIMINATION; ORGANIC FLUORINE-COMPOUNDS; NUCLEOPHILIC TRIFLUOROMETHYLATION; MEDICINAL CHEMISTRY; 1-AND 2-(TRIFLUOROMETHYL)NAPHTHALENES; BIOLOGICAL EVALUATION; SELECTIVE INHIBITORS; SYNTHETIC METHODS;
D O I：
10.1016/j.tet.2011.01.002
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：2161 / 2195
页数：35
相关论文
共 212 条
[41]   Copper-Mediated Oxidative Trifluoromethylation of Boronic Acids [J].
Chu, Lingling ;
Qing, Feng-Ling .
ORGANIC LETTERS, 2010, 12 (21) :5060-5063
[42]  
CIDNUNEZ JM, 2009, Patent No. 20099033702
[43]  
CLAFFEY MM, 2007, Patent No. 2007034282
[44]   THE TRIFLUOROMETHYLATION OF CHLOROAROMATICS USING THE COPPER-CF2BR2 - DIALKYLAMIDE REACTION SYSTEM [J].
CLARK, JH ;
DENNESS, JE ;
MCCLINTON, MA ;
WYND, AJ .
JOURNAL OF FLUORINE CHEMISTRY, 1990, 50 (03) :411-426
[45]   THE DIRECT TRIFLUOROMETHYLATION OF ARYL CHLORIDES USING BURTON REAGENT [J].
CLARK, JH ;
MCCLINTON, MA ;
BLADE, RJ .
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1988, (10) :638-639
[46]  
Clayton J., 2006, PCT Int. Appl., Patent No. [WO 2006/020879, 2006020879]
[47]  
Collins E.A., 2006, Patent No. 2006107784
[48]  
COMMONS TJ, 2008, Patent No. 200806099
[49]   The metalation of 1-and 2-(trifluoromethyl)naphthalenes: noteworthy site selectivities [J].
Cottet, F ;
Castagnetti, E ;
Schlosser, M .
SYNTHESIS-STUTTGART, 2005, (05) :798-803
[50]   Logistic flexibility in the preparation of isomeric halopyridinecarboxylic acids [J].
Cottet, F ;
Schlosser, M .
TETRAHEDRON, 2004, 60 (51) :11869-11874
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