Diastereoselective synthesis of (2S,5S)- and (2R,5S)-5-hydroxyhomopipecolic acid from S-glutamic acid. An entry to streptolutine stereoisomers.

被引：8

作者：

Herdeis, C ^{[1
]}

Held, WA ^{[1
]}

Kirfel, A ^{[1
]}

Schwabenlander, F ^{[1
]}

机构：

[1] UNIV WURZBURG,INST MINERAL & KRISTALLSTRUKTURLEHRE,D-97074 WURZBURG,GERMANY

来源：

TETRAHEDRON | 1996年 / 52卷 / 18期

关键词：

D O I：

10.1016/0040-4020(96)00282-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Starting from readily available methyl (2RS,5S) 5-(t-butyldimethylsilyloxy)-2-(2'-propenyl)-piperidine-carboxylate (1), a diastereoselective synthesis of homopipecolic acids 5a and 5b and of di-epistreptolutine derivative 10 is decribed. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：6409 / 6420

页数：12

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