Pleural Effusion Due to Use of Pioglitazone: A Case Report

被引:3
作者
Xue, Jinhui [1 ]
Liu, Wei [1 ]
Shi, Fanghong [2 ]
Zheng, Jun [1 ]
Ma, Jing [1 ]
机构
[1] Shanghai Jiao Tong Univ, Sch Med, Div Endocrinol & Metab, Affiliated Renji Hosp,Dept Internal Med, 160 Pujian Rd, Shanghai 200127, Peoples R China
[2] Shanghai Jiao Tong Univ, Affiliated Renji Hosp, Dept Pharm, Sch Med, Shanghai, Peoples R China
基金
中国国家自然科学基金;
关键词
pioglitazone; pleural effusion; edema; thiazolidinedione; case report; INSULIN; THIAZOLIDINEDIONES; EDEMA; RISK;
D O I
10.1089/met.2019.0109
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background: Pioglitazone is an effective treatment option in clinical practice for managing type 2 diabetes mellitus. It is challenged by a lot of adverse effects, primarily body weight gain, peripheral edema, as well as congestive heart failure. Case Report: This is a case of a 76-year-old woman with no evidence of cardiac disease, who developed edema as well as bilateral pleural effusion after using pioglitazone. She got a weight decrease and complete resolution of the pleural effusion after stopping use of pioglitazone and rational use of diuretics. Conclusion: Common side effects of pioglitazone have been widely reported. However, little attention was drawn on pleural effusion in diabetic patients with no pre-existing heart dysfunction. In this case, we show the use of pioglitazone results in pleural effusion, with emphasis on the clinical recognition and management.
引用
收藏
页码:168 / 171
页数:4
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