Food-induced anaphylaxis morbidity: Emergency department and hospitalization data support preventive strategies

被引：13

作者：

Tanno, Luciana Kase ^{[1
,2
,3
,4
]}

Clark, Evangeline ^{[1
]}

Mamodaly, Myriam ^{[1
]}

Cardona, Victoria ^{[5
,6
]}

Ebisawa, Motohiro ^{[7
]}

Asontegui, Ignacio ^{[8
]}

Sanchez-Borges, Mario ^{[9
]}

Santos, Alexandra F. ^{[10
,11
]}

Fiocchi, Alessandro ^{[12
]}

Worm, Margitta ^{[13
]}

Caimmi, Davide ^{[1
,2
]}

Staffeld, Patricia Latour ^{[14
]}

Muraro, Antonella ^{[15
]}

Pawankar, Ruby ^{[16
]}

Greenberger, Paul Allen ^{[17
]}

Thong, Bernard Yu-Hor ^{[18
]}

Martin, Bryan ^{[19
]}

Demoly, Pascal ^{[1
,2
,3
]}

机构：

[1] Univ Hosp Montpellier, Montpellier, France

[2] Univ Montpellier, INSERM, Desbret Inst Publ Hlth IDESP, Montpellier, France

[3] WHO Collaborating Ctr Sci Classificat Support, Montpellier, France

[4] Hosp Sirio Libanes, Sao Paulo, Brazil

[5] Hosp Valle De Hebron, Dept Internal Med, Allergy Sect, Barcelona, Spain

[6] ARADyAL Res Network, Barcelona, Spain

[7] Natl Hosp Org, Clin Res Ctr Allergy & Rheumatol, Sagamihara Natl Hosp, Sagamihara, Kanagawa, Japan

[8] Hosp Quironsalud Bizkaia Erandio, Dept Allergy & Immunol, Bilbao, Spain

[9] Ctr Med Docente La Trinidad, Allergy & Clin Immunol Dept, Caracas, Venezuela

[10] Kings Coll London, MRC, Dept Pediat Allergy, Div Asthma Allergy & Lung Biol, London, England

[11] Asthma UK Ctr Allerg Mech Asthma, London, England

[12] Bambino Gesu Childrens Hosp IRCCS, Predict & Prevent Med Res Unit, Multifactorial & Syst Dis Res Area, Rome, Italy

[13] Charite Univ Med Berlin, Dept Dermatol & Allergy, Div Allergy & Immunol, Berlin, Germany

[14] Ctr Avanzado Alergia & Asma, Santo Domingo, Dominican Rep

[15] Padua Univ Hosp, Food Allergy Ctr, Dept Woman & Child Hlth, Padua, Italy

[16] Nippon Med Sch, Tokyo, Japan

[17] Northwestern Univ, Dept Med, Div Allergy & Immunol, Feinberg Sch Med, Chicago, IL 60611 USA

[18] Tan Tock Seng Hosp, Dept Rheumatol Allergy & Immunol, Singapore, Singapore

[19] Ohio State Univ, Med & Pediat, Columbus, OH 43210 USA

来源：

PEDIATRIC ALLERGY AND IMMUNOLOGY | 2021年 / 32卷 / 08期

基金：

英国医学研究理事会;

关键词：

anaphylaxis admission; emergency visit; food allergy; food-induced anaphylaxis; hospitalization; morbidity; INTERNATIONAL CLASSIFICATION; ALLERGIC REACTIONS; CHILDREN; DISEASES; UNDERNOTIFICATION; EPIDEMIOLOGY; ADMISSIONS; MANAGEMENT; DIAGNOSIS; DEATHS;

D O I：

10.1111/pai.13578

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Background Anaphylaxis is a recognized public health issue. There is no doubt that food-induced anaphylaxis (FIA) has tremendous impact on the quality of life of patients and their families and increases direct and indirect costs. FIA is associated with increasing rates of emergency department admissions and hospitalizations and implies the risk of death. Morbidity epidemiological data are a key to tailor public health actions to this non-communicable disease. The aim of this article was to review published morbidity epidemiological data relating to FIA and potential risk factors, in order to provide evidence-based recommendations to reduce the risk of severe adverse outcomes. Methods We identified published studies available in PUBMED/MEDLINE (1966-2020), EMBASE (1980-2020) and CINAHL (1982-2020). The systematic review was carried out using MeSH terms related to FIA ED admissions and hospitalizations. Results A total of 25 articles were selected, 80% published in the last 5 years. After critical analysis of methodological and clinical characteristics reported in the data selected, we were able to propose preventive strategies. Conclusion Anaphylaxis is a recognized public health issue. FIA is associated with increasing rates of ED admissions and hospitalizations and imply in risk of death. More than reviewing and critically interpreting the key patterns related to FIA morbidity published data, we proposed strategies in order to promote quality care of patients suffering from FIA. Our World Health Organization Collaborative Center is deeply involved in this process, and we believe that the proposed strategies will inform future healthcare policies on anaphylaxis. The long-term objective would be to improve clinical care and quality of life of patients and their families, and develop risk-stratified, cost-effective preventive measures.

引用

页码：1730 / 1742

页数：13

共 74 条

[21] Anaphylaxis fatalities and admissions in Australia [J].