Transformation of Chlamydia: current approaches and impact on our understanding of chlamydial infection biology

被引：17

作者：

Rahnama, Mostafa ^{[1
]}

Fields, Kenneth A. ^{[1
]}

机构：

[1] Univ Kentucky, Coll Med, Dept Microbiol Immunol & Mol Genet, Lexington, KY 40536 USA

来源：

MICROBES AND INFECTION | 2018年 / 20卷 / 7-8期

基金：

美国国家卫生研究院;

关键词：

Transformation; Genetics; Mutagenesis; Pathogenesis; OBLIGATE INTRACELLULAR PATHOGEN; INCLUSION MEMBRANE-PROTEINS; IN-VITRO; TRACHOMATIS SURVIVAL; GENETIC-ANALYSIS; EXPRESSION; MURIDARUM; PERSISTENCE; MUTAGENESIS; SECRETION;

D O I：

10.1016/j.micinf.2018.01.002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The intonation "The king is dead, long live the king" aptly describes the state of Chlamydia research. Genetic-based approaches are rapidly replacing correlative strategies to provide new insights. We describe how current transformation technologies are enhancing progress in understanding Chlamydia infection biology and present key opportunities for further development. (C) 2018 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

引用

页码：445 / 450

页数：6

共 77 条

[1] The chlamydial developmental cycle [J].

AbdelRahman, YM ;

Belland, RJ .

FEMS MICROBIOLOGY REVIEWS, 2005, 29 (05) :949-959

[2] Expression of the Effector Protein IncD in Chlamydia trachomatis Mediates Recruitment of the Lipid Transfer Protein CERT and the Endoplasmic Reticulum-Resident Protein VAPB to the Inclusion Membrane [J].

Agaisse, Herve ;

Derre, Isabelle .

INFECTION AND IMMUNITY, 2014, 82 (05) :2037-2047

[3] A C-trachomatis Cloning Vector and the Generation of C-trachomatis Strains Expressing Fluorescent Proteins under the Control of a C-trachomatis Promoter [J].

Agaisse, Herve ;

Derre, Isabelle .

PLOS ONE, 2013, 8 (02)

[4] Emancipating Chlamydia: Advances in the Genetic Manipulation of a Recalcitrant Intracellular Pathogen [J].

Bastidas, Robert J. ;

Valdivia, Raphael H. .

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 2016, 80 (02) :411-427

[5] Expression and Targeting of Secreted Proteins from Chlamydia trachomatis [J].

Bauler, Laura D. ;

Hackstadt, Ted .

JOURNAL OF BACTERIOLOGY, 2014, 196 (07) :1325-1334

[6] Advances in genetic manipulation of obligate intracellular bacterial pathogens [J].

Beare, Paul A. ;

Sandoz, Kelsi M. ;

Omsland, Anders ;

Rockey, Daniel D. ;

Heinzen, Robert A. .

FRONTIERS IN MICROBIOLOGY, 2011, 2

[7] Transformation and isolation of allelic exchange mutants of Chlamydia psittaci using recombinant DNA introduced by electroporation [J].

Binet, Rachel ;

Maurelli, Anthony T. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (01) :292-297

[8] Interrogating Genes That Mediate Chlamydia trachomatis Survival in Cell Culture Using Conditional Mutants and Recombination [J].

Brothwell, Julie A. ;

Muramatsu, Matthew K. ;

Toh, Evelyn ;

Rockey, Daniel D. ;

Putman, Timothy E. ;

Barta, Michael L. ;

Hefty, P. Scott ;

Suchland, Robert J. ;

Nelson, David E. .

JOURNAL OF BACTERIOLOGY, 2016, 198 (15) :2131-2139

[9] Development of Shuttle Vectors for Transformation of Diverse Rickettsia Species [J].

Burkhardt, Nicole Y. ;

Baldridge, Gerald D. ;

Williamson, Phillip C. ;

Billingsley, Peggy M. ;

Heu, Chan C. ;

Felsheim, Roderick F. ;

Kurtti, Timothy J. ;

Munderloh, Ulrike G. .

PLOS ONE, 2011, 6 (12)

[10] Bioluminescence Imaging of Chlamydia muridarum Ascending Infection in Mice [J].

Campbell, Jessica ;

Huang, Yumeng ;

Liu, Yuanjun ;

Schenken, Robert ;

Arulanandam, Bernard ;

Zhong, Guangming .

PLOS ONE, 2014, 9 (07)

← 1 2 3 4 5 6 7 8 →