Is the measurement of free IGF-I more indicative than that of total IGF-I in the evaluation of the biological activity of the GH/IGF-I axis?

被引：31

作者：

Janssen, JAMJL ^{[1
]}

Lamberts, SWJ ^{[1
]}

机构：

[1] Erasmus Univ, Hosp Dijkzigt, Dept Internal Med 3, NL-3015 GD Rotterdam, Netherlands

来源：

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION | 1999年 / 22卷 / 04期

关键词：

D O I：

10.1007/BF03343563

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：313 / 315

页数：3

共 17 条

[1]

Blum W, 1996, GROWTH HORMONE ADULT, P48

[2] Recovery of growth hormone release from suppression by exogenous insulin-like growth factor I (IGF-I): Evidence for a suppressive action of free rather than bound IGF-I [J].

Chapman, IM ;

Hartman, ML ;

Pieper, KS ;

Skiles, EH ;

Pezzoli, SS ;

Hintz, RL ;

Thorner, MO .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1998, 83 (08) :2836-2842

[3]

CHESTNUT R, 1997, 79 ANN M END SOC MIN

[4] The role of the insulin-like growth factor binding proteins and the IGFBP proteases in modulating IGF action [J].

CollettSolberg, PF ;

Cohen, P .

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 1996, 25 (03) :591-&

[5]

EKINS R, 1992, CLIN CHEM, V38, P1289

[6] INSULIN-LIKE GROWTH-FACTORS AND INSULIN - COMPARATIVE ASPECTS [J].

FROESCH, ER ;

ZAPF, J .

DIABETOLOGIA, 1985, 28 (08) :485-493

[7] Increased levels of circulating free insulin-like growth factors in patients with non-islet cell tumour hypoglycaemia [J].

Frystyk, J ;

Skjærbæk, C ;

Zapf, J ;

Orskov, H .

DIABETOLOGIA, 1998, 41 (05) :589-594

[8] FREE INSULIN-LIKE GROWTH-FACTORS (IGF-I AND IGF-II) IN HUMAN SERUM [J].

FRYSTYK, J ;

SKJAERBAEK, C ;

DINESEN, B ;

ORSKOV, H .

FEBS LETTERS, 1994, 348 (02) :185-191

[9] FREE INSULIN-LIKE GROWTH-FACTORS IN HUMAN OBESITY [J].

FRYSTYK, J ;

VESTBO, E ;

SKJAERBAEK, C ;

MOGENSEN, CE ;

ORSKOV, H .

METABOLISM-CLINICAL AND EXPERIMENTAL, 1995, 44 (10) :37-44

[10] THE FREE-FORM OF INSULIN-LIKE GROWTH-FACTOR-I INCREASES IN CIRCULATION DURING NORMAL HUMAN-PREGNANCY [J].

HASEGAWA, T ;

HASEGAWA, Y ;

TAKADA, M ;

TSUCHIYA, Y .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1995, 80 (11) :3284-3286

← 1 2 →