Systematic evaluation on the effectiveness of conjugated linoleic acid in human health

被引:108
作者
Fuke, Gitane [1 ]
Nornberg, Jose Laerte [1 ]
机构
[1] Ctr Ciencias Rurais Predio, Dept Ciencia & Tecnol Alimentos Endereco, Campus Univ, Santa Maria, RS, Brazil
关键词
Conjugated linoleic acid; benefit; dairy; health; REDUCES BODY-FAT; BREAST-CANCER; DIETARY; CLA; SUPPLEMENTATION; RISK; MILK; BEEF; FOOD; ATHEROSCLEROSIS;
D O I
10.1080/10408398.2012.716800
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
The term CLA (conjugated linoleic acid) corresponds to a mixture of positional and geometric isomers of linoleic acid. Two of these isomers (9c, 11t and 10t, 12c) have biological activity. The milk and dairy products are the most abundant source of conjugated linoleic acid, which refers to a group of positional and geometric isomers of CLA (CLA 18:2 cis-9, cis-12). The following research aims to approach aspects regarding the CLA, as well as its relationship with diseases. Conjugated linoleic acids have been studied for their beneficial effects in the prevention and treatment of many diseases, including obesity, cancer, diabetes, and cardiovascular diseases. Scientific information put together the physiological properties of CLA, which serves as inputs to claim their potential as functional ingredients to be used in the prevention and control of several chronic metabolic disorders.
引用
收藏
页码:1 / 7
页数:7
相关论文
共 72 条
  • [61] Conjugated linoleic acid reduces body fat in healthy exercising humans
    Thom, E
    Wadstein, J
    Gudmundsen, O
    [J]. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2001, 29 (05) : 392 - 396
  • [62] Toomey S, 2003, BIOCHEM SOC T, V31, P1075, DOI 10.1042/BST0311075
  • [63] Tricon S, 2004, AM J CLIN NUTR, V80, P614
  • [64] Immunological and metabolic effects of cis-9, trans-11-conjugated linoleic acid in subjects with birch pollen allergy
    Turpeinen, Anu A.
    Ylonen, Niina
    von Willebrand, Eva
    Basu, Samar
    Aro, Antti
    [J]. BRITISH JOURNAL OF NUTRITION, 2008, 100 (01) : 112 - 119
  • [65] Intake of conjugated linoleic acid, fat, and other fatty acids in relation to postmenopausal breast cancer: the Netherlands Cohort Study on Diet and Cancer
    Voorrips, LE
    Brants, HAM
    Kardinaal, AFM
    Hiddink, GJ
    van den Brandt, PA
    Goldbohm, RA
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 2002, 76 (04) : 873 - 882
  • [66] Conjugated linoleic acids: are they beneficial or detrimental to health?
    Wahle, KWJ
    Heys, SD
    Rotondo, D
    [J]. PROGRESS IN LIPID RESEARCH, 2004, 43 (06) : 553 - 587
  • [67] Conjugated linoleic acid and obesity control: efficacy and mechanisms
    Wang, YW
    Jones, PJH
    [J]. INTERNATIONAL JOURNAL OF OBESITY, 2004, 28 (08) : 941 - 955
  • [68] Conjugated linoleic acid: Implications for human health
    Whigham, LD
    Cook, ME
    Atkinson, RL
    [J]. PHARMACOLOGICAL RESEARCH, 2000, 42 (06) : 503 - 510
  • [69] Conjugated linoleic acid reduces early aortic atherosclerosis greater than linoleic acid in hypercholesterolemic hamsters
    Wilson, TA
    Nicolosi, RJ
    Chrysam, M
    Kritchevsky, D
    [J]. NUTRITION RESEARCH, 2000, 20 (12) : 1795 - 1805
  • [70] Dietary sources of unsaturated fatty acids for animals and their transfer into meat, milk and eggs: A review
    Woods, Vanessa B.
    Fearon, Anna M.
    [J]. LIVESTOCK SCIENCE, 2009, 126 (1-3) : 1 - 20