Systematic evaluation on the effectiveness of conjugated linoleic acid in human health

被引:108
作者
Fuke, Gitane [1 ]
Nornberg, Jose Laerte [1 ]
机构
[1] Ctr Ciencias Rurais Predio, Dept Ciencia & Tecnol Alimentos Endereco, Campus Univ, Santa Maria, RS, Brazil
关键词
Conjugated linoleic acid; benefit; dairy; health; REDUCES BODY-FAT; BREAST-CANCER; DIETARY; CLA; SUPPLEMENTATION; RISK; MILK; BEEF; FOOD; ATHEROSCLEROSIS;
D O I
10.1080/10408398.2012.716800
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
The term CLA (conjugated linoleic acid) corresponds to a mixture of positional and geometric isomers of linoleic acid. Two of these isomers (9c, 11t and 10t, 12c) have biological activity. The milk and dairy products are the most abundant source of conjugated linoleic acid, which refers to a group of positional and geometric isomers of CLA (CLA 18:2 cis-9, cis-12). The following research aims to approach aspects regarding the CLA, as well as its relationship with diseases. Conjugated linoleic acids have been studied for their beneficial effects in the prevention and treatment of many diseases, including obesity, cancer, diabetes, and cardiovascular diseases. Scientific information put together the physiological properties of CLA, which serves as inputs to claim their potential as functional ingredients to be used in the prevention and control of several chronic metabolic disorders.
引用
收藏
页码:1 / 7
页数:7
相关论文
共 72 条
  • [51] Risérus U, 2004, AM J CLIN NUTR, V80, P279
  • [52] Serum fatty acids and breast cancer incidence
    Rissanen, H
    Knekt, P
    Järvinen, R
    Salminen, I
    Hakulinen, T
    [J]. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2003, 45 (02): : 168 - 175
  • [53] Estimation of conjugated linoleic acid intake by written dietary assessment methodologies underestimates actual intake evaluated by food duplicate methodology
    Ritzenthaler, KL
    McGuire, MK
    Falen, R
    Shultz, TD
    Dasgupta, N
    McGuire, MA
    [J]. JOURNAL OF NUTRITION, 2001, 131 (05) : 1548 - 1554
  • [54] Roche HM, 2001, NUTR RES REV, V14, P173, DOI [10.1079/095442201108729187, 10.1079/NRR200122]
  • [55] Isomer-specific antidiabetic properties of conjugated linoleic acid - Improved glucose tolerance, skeletal muscle insulin action, and UCP-2 gene expression
    Ryder, JW
    Portocarrero, CP
    Song, XM
    Cui, L
    Yu, M
    Combatsiaris, T
    Galuska, D
    Bauman, DE
    Barbano, DM
    Charron, MJ
    Zierath, JR
    Houseknecht, KL
    [J]. DIABETES, 2001, 50 (05) : 1149 - 1157
  • [56] Effects of conjugated linoleic acid on animal metabolism: advances in research and perspectives for the future
    Santos-Zago, Lilia Ferreira
    Botelho, Adriana Prais
    de Oliveira, Admar Costa
    [J]. REVISTA DE NUTRICAO-BRAZILIAN JOURNAL OF NUTRITION, 2008, 21 (02): : 195 - 221
  • [57] Sebedio J L, 1999, Curr Opin Clin Nutr Metab Care, V2, P499, DOI 10.1097/00075197-199911000-00012
  • [58] Conjugated Linoleic Acid (CLA) content of meat from three muscles of Massese suckling lambs slaughtered at different weights
    Serra, A.
    Mele, M.
    La Comba, F.
    Conte, G.
    Buccioni, A.
    Secchiari, P.
    [J]. MEAT SCIENCE, 2009, 81 (02) : 396 - 404
  • [59] Obesity remains under diagnosed in English hospital in-patients
    Sharma, Vishwamitra
    Braithwaite, Antonia
    Harger, Simon
    Finer, Nick
    [J]. OBESITY RESEARCH & CLINICAL PRACTICE, 2009, 3 (01) : 17 - 20
  • [60] Conjugated linoleic acids exhibit a strong fat-to-lean partitioning effect, reduce serum VLDL lipids and redistribute tissue lipids in food-restricted rats
    Stangl, GI
    [J]. JOURNAL OF NUTRITION, 2000, 130 (05) : 1140 - 1146