ZrOCl2•8H2O/SiO2: An efficient and recyclable catalyst for the preparation of coumarin derivatives by Pechmann condensation reaction

被引：79

作者：

Karami, Bahador ^{[1
]}

Kiani, Mahtab ^{[1
]}

机构：

[1] Univ Yasuj, Dept Chem, Yasuj 7591874831, Iran

来源：

CATALYSIS COMMUNICATIONS | 2011年 / 14卷 / 01期

关键词：

Coumarin; Recyclable catalysts; Silica gel; Zirconyl chloride octahydrate; Solvent-free conditions; SOLVENT-FREE CONDITIONS; MICROWAVE IRRADIATION; 4-SUBSTITUTED COUMARINS; REUSABLE CATALYST; HIGHLY EFFICIENT; AMINES; CHLORIDE; INDOLES; FACILE; ZRCL4;

D O I：

10.1016/j.catcom.2011.07.002

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Silica gel supported zirconyl chloride octahydrate was found to be an efficient and recyclable catalyst for the synthesis of a series of biologically important molecules in high turnover numbers and rates. Several substituted coumarins can be prepared in high yield and purity by direct reaction of beta-keto esters and phenol derivatives in the presence of a catalytic amount of ZrOCl(2 center dot)8H(2)O/SiO2 as Lewis acid and at ambient temperature under solvent-free conditions. This method which is called Pechmann condensation is a very easy and a rapid reaction for the synthesis of coumarin derivatives. (C) 2011 Elsevier B.V. All rights reserved.

引用

页码：62 / 67

页数：6

共 35 条

[1] Samarium(III) catalyzed one-pot construction of coumarins [J].