Interference-contrast optical activity: a new technique for probing the chirality of anisotropic samples and more

被引：1

作者：

Cameron, R. P. ^{[1
,2
]}

Vogl, U. ^{[3
]}

Trautmann, N. ^{[3
]}

机构：

[1] SUPA, Glasgow G4 0NG, Lanark, Scotland

[2] Univ Strathclyde, Dept Phys, Glasgow G4 0NG, Lanark, Scotland

[3] Carl Zeiss, Corp Res & Technol, Carl Zeiss Str 22, D-73447 Oberkochen, Germany

来源：

ROYAL SOCIETY OPEN SCIENCE | 2020年 / 7卷 / 05期

关键词：

chirality; optical activity; polarization; polarimetry; microscopy; DIC; DOWN POLARIMETRY CRDP; CIRCULAR-DICHROISM; APPARATUS HAUP; BIREFRINGENCE; CRYSTALS; ROTATION;

D O I：

10.1098/rsos.192201

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We introduce interference-contrast optical activity (ICOA) as a new technique for probing the chirality of anisotropic samples and more. ICOA could underpin a new class of 'chiral microscopes', with potential applications spanning the range of chirality and beyond. Two possible versions of ICOA are described explicitly; one designed to probe the optical rotation of a transparent sample regardless of the sample's linear birefringence (ICOA-OR) and another designed to probe gradients in the optical rotation of a transparent sample (ICOA-GOR). Simulated results for alpha-quartz lead us to suggest that ICOA-GOR might be applied to help monitor the growth of chiral crystals in the pharmaceutical industry. Possible directions for future research are highlighted.

引用

页数：17

共 22 条

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