Intrasession repeatability of ocular anatomical measurements obtained with a multidiagnostic device in healthy eyes

Background: To evaluate the intrasession repeatability of anterior chamber depth (ACD), central (CCT) and peripheral corneal thickness (PCT), white-to-white diameter (WTW), and irido-corneal angle (IA) measurements obtained with a multidiagnostic device in healthy eyes. Methods: A total of 107 eyes of 107 patients ranging in age from 23 to 65 years were examined with the VX120 system (Visionix-Luneau Technologies). Three consecutive measurements were obtained with this device to assess the intrasession repeatability of ACD, CCT, PCT at different nasal and temporal locations, WTW, and nasal and temporal IA. Data analysis included the calculation of within-subject standard deviation (S-w), intrasubject precision (1.96xS(w)), coefficient of variation (CV) and intraclass correlation coefficient (ICC). Results: The S-w and CV for ACD was 0.03 mm and 1.16%, respectively, with an ICC of 0.992. The Sw values for central and peripheral pachymetric measurements were below 9 mu m, with CV of less than 1.6% and ICC of 0.976 or higher. For IA measurements, S-w values of 0.84 or lower were found, with a CV between 1 and 2%, and an ICC of more than 0.970. The S-w for WTW was 0.24 mm and the CV was 1.95%. No statistically significant correlations were found between any anatomical parameter evaluated and their S-w and CV values associated (-0.220 <= r <= 0.204, p >= 0.125). Conclusions: The VX120 system is able to provide repeatable measurements of anatomical parameters in healthy eyes. Inter-observer repeatability should be evaluated in future studies.