Phytosterols - health benefits and potential concerns: a review

被引:239
作者
Kritchevsky, D [1 ]
Chen, SC [1 ]
机构
[1] Wistar Inst Anat & Biol, Philadelphia, PA 19104 USA
基金
美国国家卫生研究院;
关键词
atherosclerosis; cholesterol; sitosterol; campesterol; phytosterols;
D O I
10.1016/j.nutres.2005.02.003
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Phytosterols have been used as blood cholesterol-lowering agents for the last half century. They have been shown to be effective and safe. Originally presented as a pharmaceutical formulation, phytosterols are now being added to an increasing variety of foodstuffs. On occasion, questions have arisen concerning their safety, but at the present time and at the current level of usage, no adverse effects have been observed. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码:413 / 428
页数:16
相关论文
共 113 条
[31]   CHOLESTEROL FEEDING INCREASES PLASMA AND AORTIC TISSUE CHOLESTEROL OXIDE LEVELS IN PARALLEL - FURTHER EVIDENCE FOR THE ROLE OF CHOLESTEROL OXIDATION IN ATHEROSCLEROSIS [J].
HODIS, HN ;
CRAWFORD, DW ;
SEVANIAN, A .
ATHEROSCLEROSIS, 1991, 89 (2-3) :117-126
[32]  
Howell TJ, 1998, J LIPID RES, V39, P892
[33]   Mechanisms of phytosterolemia in stroke-prone spontaneously hypertensive and WKY rats [J].
Ikeda, I ;
Nakagiri, H ;
Sugano, M ;
Ohara, S ;
Hamada, T ;
Nonaka, M ;
Imaizumi, K .
METABOLISM-CLINICAL AND EXPERIMENTAL, 2001, 50 (11) :1361-1368
[34]   STEROL COMPOSITION OF 19 VEGETABLE OILS [J].
ITOH, T ;
TAMURA, T ;
MATSUMOT.T .
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1973, 50 (04) :122-125
[35]   Plant sterols, health claims and strategies to reduce cardiovascular disease risk [J].
Jenkins, DJA ;
Kendall, CWC .
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 1999, 18 (06) :559-562
[36]  
Jones PJ, 2000, J LIPID RES, V41, P697
[37]   Plant sterol esters lower plasma lipids and most carotenoids in mildly hypercholesterolemic adults [J].
Judd, JT ;
Baer, DJ ;
Chen, SC ;
Clevidence, BA ;
Muesing, RA ;
Kramer, M ;
Meijer, GW .
LIPIDS, 2002, 37 (01) :33-42
[38]  
KAGAN A, 1982, STROKE, V13, P62
[39]   Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels [J].
Katan, MB ;
Grundy, SM ;
Jones, P ;
Law, M ;
Miettinen, T ;
Paoletti, R .
MAYO CLINIC PROCEEDINGS, 2003, 78 (08) :965-978
[40]  
KEYS A, 1997, CIRCULATION S1, V41, P1