Phytosterols - health benefits and potential concerns: a review

被引:239
作者
Kritchevsky, D [1 ]
Chen, SC [1 ]
机构
[1] Wistar Inst Anat & Biol, Philadelphia, PA 19104 USA
基金
美国国家卫生研究院;
关键词
atherosclerosis; cholesterol; sitosterol; campesterol; phytosterols;
D O I
10.1016/j.nutres.2005.02.003
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Phytosterols have been used as blood cholesterol-lowering agents for the last half century. They have been shown to be effective and safe. Originally presented as a pharmaceutical formulation, phytosterols are now being added to an increasing variety of foodstuffs. On occasion, questions have arisen concerning their safety, but at the present time and at the current level of usage, no adverse effects have been observed. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码:413 / 428
页数:16
相关论文
共 113 条
[1]  
AHRENS EH, 1957, LANCET, V1, P943
[2]   DIETARY CONTROL OF SERUM LIPIDS IN RELATION TO ATHEROSCLEROSIS [J].
AHRENS, EH ;
HIRSCH, J ;
INSULL, W ;
TSALTAS, TT ;
BLOMSTRAND, R ;
PETERSON, ML .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1957, 164 (17) :1905-1911
[3]   Plant sterol ester-enriched spread lowers plasma total and LDL cholesterol in children with familial hypercholesterolemia [J].
Amundsen, ÅL ;
Ose, L ;
Nenseter, MS ;
Ntanios, FY .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2002, 76 (02) :338-344
[4]  
AMUNDSEN AL, 2004, EUR J CLIN NUTR
[5]   Safety evaluation of phytosterol esters. Part 5. Faecal short-chain fatty acid and microflora content, faecal bacterial enzyme activity and serum female sex hormones in healthy normolipidaemic volunteers consuming a controlled diet either with or without a phytosterol ester-enriched margarine [J].
Ayesh, R ;
Weststrate, JA ;
Drewitt, PN ;
Hepburn, PA .
FOOD AND CHEMICAL TOXICOLOGY, 1999, 37 (12) :1127-1138
[6]   Safety evaluation of phytosterol esters.: Part 1.: Assessment of oestrogenicity using a combination of in vivo and in vitro assays [J].
Baker, VA ;
Hepburn, PA ;
Kennedy, SJ ;
Jones, PA ;
Lea, LJ ;
Sumpter, JP ;
Ashby, J .
FOOD AND CHEMICAL TOXICOLOGY, 1999, 37 (01) :13-22
[7]  
Bean GA., 1973, Ads Lipid Res, V11, P193
[8]  
Berger GMB, 1998, J LIPID RES, V39, P1046
[9]   THE EFFECTS OF CERTAIN VEGETABLE AND ANIMAL FATS ON THE PLASMA LIPIDS OF HUMANS [J].
BEVERIDGE, JMR ;
CONNELL, WF ;
MAYER, GA ;
FIRSTBROOK, JB ;
DEWOLFE, MS .
JOURNAL OF NUTRITION, 1955, 56 (02) :311-320
[10]  
BEVERIDGE JMR, 1956, CAN J BIOCHEM PHYS, V34, P441