Sliver nanoparticles@carbon dots for synergistic antibacterial activity

被引:25
作者
Wang, Panyong [1 ,2 ]
Song, Yizhi [2 ]
Mei, Qian [1 ,2 ]
Dong, Wen-Fei [1 ,2 ]
Li, Li [1 ,2 ,3 ]
机构
[1] Univ Sci & Technol China, Sch Biomed Engn Suzhou, Div Life Sci & Med, Hefei 230026, Peoples R China
[2] Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, CAS Key Lab Biomed Diagnost, Suzhou 215163, Peoples R China
[3] Zhengzhou Inst Biomed Engn & Technol, Zhengzhou 450001, Henan, Peoples R China
基金
中国科学院基金;
关键词
AgNPs; Carbon dots; ROS; Composites; Antibacterial activity; SILVER NANOPARTICLES; AGGREGATION; MECHANISMS; AGENT;
D O I
10.1016/j.apsusc.2022.154125
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A novel composite material named sliver nanoparticles@carbon dots (AgNPs/CDs) was fabricated with CDs as the capping agents through one simple method. The images of TEM showed that CDs were embedded in the gaps of AgNPs and the as-prepared AgNPs/CDs can be self assembled into nanochains through electrosatic interaction between silver nanoparticles and carbon dots. With higher redox properties than AgNPs, the as-prepared com-posites exhibited excellent synergistic antibacterial performance against Gram-positive bacterium and Gram-negative bacterium in the antibacterial assays, which indicates potential application as an effective antibacte-rial material. And the results of antibacterial assy showed that the minimum inhibitory concentrations (MIC) of AgNPs/CDs were 40 mu g/mL for E. coli and 20 mu g/mL for S. aureus in LB medium. In addition, the oxidative stress induced by AgNPs/CDs-mediated reactive oxygen species further confirmed good application prospects in antibacterial.
引用
收藏
页数:8
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