How the size distribution of magnetic nanoparticles determines their magnetic particle imaging performance

被引：154

作者：

Eberbeck, D. ^{[1
]}

Wiekhorst, F. ^{[1
]}

Wagner, S. ^{[2
]}

Trahms, L. ^{[1
]}

机构：

[1] Phys Tech Bundesanstalt, D-10587 Berlin, Germany

[2] Charite, D-10117 Berlin, Germany

来源：

APPLIED PHYSICS LETTERS | 2011年 / 98卷 / 18期

关键词：

D O I：

10.1063/1.3586776

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

Spatial and temporal resolution of magnetic particle imaging (MPI), a powerful technique for biomedical imaging, depends crucially on the magnetic properties of the magnetic nanoparticle (MNP) tracer. The authors establish the relation of the static and the dynamic magnetization behavior of various MNP preparations to their MPI performance. While MNPs with a mean diameter of 6 nm achieve only 0.2% of the theoretical maximum amplitude of the third harmonic (at 25 kA/m drive field strength), those with 19 nm diameter attain 57%. The good performance of Resovist, a clinically approved contrast agent for magnetic resonance imaging, is explained by the presence of MNP aggregates. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3586776]

引用

页数：3

共 14 条

[1]

Braun K.-F., ARXIV10023739

[2] Aggregation behaviour of magnetic nanoparticle suspensions investigated by magnetorelaxometry [J].