Emerging antibacterial and antiviral drugs for treating respiratory tract infections
被引:4
作者:
Mantero, Marco
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Univ Milan, Dept Pathophysiol & Transplantat, Dept Internal Med, Resp Unit, Via Francesco Sforza 35, Milan, Italy
IRCCS Fdn Ca Granda Osped Maggiore Policlin, Reg Adult Cyst Fibrosis Ctr, Via Francesco Sforza 35, Milan, ItalyUniv Milan, Dept Pathophysiol & Transplantat, Dept Internal Med, Resp Unit, Via Francesco Sforza 35, Milan, Italy
Mantero, Marco
[1
,2
]
Rogliani, Paola
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机构:
Univ Roma Tor Vergata, Dept Syst Med, Resp Unit, Rome, ItalyUniv Milan, Dept Pathophysiol & Transplantat, Dept Internal Med, Resp Unit, Via Francesco Sforza 35, Milan, Italy
Rogliani, Paola
[3
]
Cazzola, Mario
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机构:
Univ Roma Tor Vergata, Dept Syst Med, Resp Unit, Rome, ItalyUniv Milan, Dept Pathophysiol & Transplantat, Dept Internal Med, Resp Unit, Via Francesco Sforza 35, Milan, Italy
Cazzola, Mario
[3
]
Blasi, Francesco
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机构:
Univ Milan, Dept Pathophysiol & Transplantat, Dept Internal Med, Resp Unit, Via Francesco Sforza 35, Milan, Italy
IRCCS Fdn Ca Granda Osped Maggiore Policlin, Reg Adult Cyst Fibrosis Ctr, Via Francesco Sforza 35, Milan, ItalyUniv Milan, Dept Pathophysiol & Transplantat, Dept Internal Med, Resp Unit, Via Francesco Sforza 35, Milan, Italy
Blasi, Francesco
[1
,2
]
Di Pasquale, Marta
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milan, Dept Pathophysiol & Transplantat, Dept Internal Med, Resp Unit, Via Francesco Sforza 35, Milan, Italy
IRCCS Fdn Ca Granda Osped Maggiore Policlin, Reg Adult Cyst Fibrosis Ctr, Via Francesco Sforza 35, Milan, ItalyUniv Milan, Dept Pathophysiol & Transplantat, Dept Internal Med, Resp Unit, Via Francesco Sforza 35, Milan, Italy
Di Pasquale, Marta
[1
,2
]
机构:
[1] Univ Milan, Dept Pathophysiol & Transplantat, Dept Internal Med, Resp Unit, Via Francesco Sforza 35, Milan, Italy
[2] IRCCS Fdn Ca Granda Osped Maggiore Policlin, Reg Adult Cyst Fibrosis Ctr, Via Francesco Sforza 35, Milan, Italy
[3] Univ Roma Tor Vergata, Dept Syst Med, Resp Unit, Rome, Italy
Introduction: Management of LRTI is becoming more frequently challenging since the emergence of multidrug resistance bacteria and the increase of severe viral infection, reducing the number of available effective drugs. The clinical evaluation of new therapeutic associations is mandatory to cope with the increases in resistance, in association with better infection control and antimicrobial policies. Areas covered: We searched Pubmed in English language of phase I, II, III clinical trials and approved treatments for LRTI, between 2006 and 2016. Expert opinion:Development of new molecules or new combinations regimens are very important for patients with severe infections and in specific subgroups of patients like CF and bronchiectatic patients. Standardized protocols for antibiotic stewardship in difficult-to-treat infections are the next step. Moreover, non-antibiotic treatments and preventive strategies as vaccination need to be part of clinical practice.
机构:
Univ Toronto, Sunnybrook Hlth Sci Ctr, Med Outcomes & Res Econ MORE Res Grp, Toronto, ON, CanadaUniv Toronto, Sunnybrook Hlth Sci Ctr, Med Outcomes & Res Econ MORE Res Grp, Toronto, ON, Canada
Abraha, Haben Y.
Lanctot, Krista L.
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Univ Toronto, Sunnybrook Hlth Sci Ctr, Med Outcomes & Res Econ MORE Res Grp, Toronto, ON, CanadaUniv Toronto, Sunnybrook Hlth Sci Ctr, Med Outcomes & Res Econ MORE Res Grp, Toronto, ON, Canada
Lanctot, Krista L.
Paes, Bosco
论文数: 0引用数: 0
h-index: 0
机构:
McMaster Univ, Dept Pediat, Div Neonatol, Hamilton, ON, CanadaUniv Toronto, Sunnybrook Hlth Sci Ctr, Med Outcomes & Res Econ MORE Res Grp, Toronto, ON, Canada
机构:
Univ Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
Fdn IRCCS Ca Granda Osped Maggiore Policlin, Adult Cyst Fibrosis Ctr, Milan, ItalyUniv Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
Aliberti, Stefano
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Reyes, Luis F.
Faverio, Paola
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机构:
Univ Milano Bicocca, AO San Gerardo, Sch Med & Surg, Monza, ItalyUniv Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
Faverio, Paola
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Sotgiu, Giovanni
Dore, Simone
论文数: 0引用数: 0
h-index: 0
机构:
Univ Sassari, Clin Epidemiol & Med Stat Unit, Dept Biomed Sci, Res Med Educ & Profess Dev Unit,AOU Sassari, Sassari, ItalyUniv Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
Dore, Simone
Rodriguez, Alejandro H.
论文数: 0引用数: 0
h-index: 0
机构:
Hosp Univ Joan XXIII, Crit Care Med, Tarragona, SpainUniv Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
Rodriguez, Alejandro H.
Soni, Nilam J.
论文数: 0引用数: 0
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机构:
Univ Texas Hlth Sci Ctr San Antonio, Div Pulm Dis & Crit Care Med, San Antonio, TX 78229 USA
South Texas Vet Hlth Care Syst, Div Pulm Dis & Crit Care Med, San Antonio, TX USAUniv Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
Soni, Nilam J.
Restrepo, Marcos I.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Texas Hlth Sci Ctr San Antonio, Div Pulm Dis & Crit Care Med, San Antonio, TX 78229 USA
South Texas Vet Hlth Care Syst, Div Pulm Dis & Crit Care Med, San Antonio, TX USAUniv Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
机构:
Univ Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, ItalyUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Aliberti, Stefano
Cilloniz, Catia
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机构:
Hosp Clin Barcelona, Ciberes, IDIBAPS, Barcelona, SpainUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Cilloniz, Catia
Chalmers, James D.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Dundee, Ninewells Hosp & Med Sch, Tayside Resp Res Grp, Dundee DD1 9SY, ScotlandUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Chalmers, James D.
Zanaboni, Anna Maria
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milan, Comp Sci Dept, I-20122 Milan, ItalyUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Zanaboni, Anna Maria
Cosentini, Roberto
论文数: 0引用数: 0
h-index: 0
机构:
Osped Maggiore Policlin, Emergency Med Dept, IRCCS Fdn Ca Granda, Milan, ItalyUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Cosentini, Roberto
Tarsia, Paolo
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h-index: 0
机构:
Univ Milan, Dept Pathophysiol & Transplantat, IRCCS Fdn Ca Granda Osped Maggiore Policlin, I-20122 Milan, ItalyUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Tarsia, Paolo
Pesci, Alberto
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机构:
Univ Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, ItalyUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Pesci, Alberto
Blasi, Francesco
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h-index: 0
机构:
Univ Milan, Dept Pathophysiol & Transplantat, IRCCS Fdn Ca Granda Osped Maggiore Policlin, I-20122 Milan, ItalyUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Blasi, Francesco
Torres, Antoni
论文数: 0引用数: 0
h-index: 0
机构:
Hosp Clin Barcelona, Ciberes, IDIBAPS, Barcelona, SpainUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
机构:
Univ Milan, IRCCS Fdn Ca Granda Osped Maggiore Policlin, Dipartimento Toraco Polmonare & Cardiocircolatori, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Di Pasquale, Marta
Zanaboni, Anna Maria
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milan, Dept Comp Sci, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Zanaboni, Anna Maria
Cosentini, Roberto
论文数: 0引用数: 0
h-index: 0
机构:
Osped Maggiore Policlin, IRCCS Fdn Ca Granda, Dept Emergency Med, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Cosentini, Roberto
Brambilla, Anna Maria
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h-index: 0
机构:
Osped Maggiore Policlin, IRCCS Fdn Ca Granda, Dept Emergency Med, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Brambilla, Anna Maria
Seghezzi, Sonia
论文数: 0引用数: 0
h-index: 0
机构:
Osped Maggiore Policlin, IRCCS Fdn Ca Granda, Dept Emergency Med, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Seghezzi, Sonia
Tarsia, Paolo
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milan, IRCCS Fdn Ca Granda Osped Maggiore Policlin, Dipartimento Toraco Polmonare & Cardiocircolatori, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Tarsia, Paolo
Mantero, Marco
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Mantero, Marco
Blasi, Francesco
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milan, IRCCS Fdn Ca Granda Osped Maggiore Policlin, Dipartimento Toraco Polmonare & Cardiocircolatori, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
机构:
Univ Toronto, Sunnybrook Hlth Sci Ctr, Med Outcomes & Res Econ MORE Res Grp, Toronto, ON, CanadaUniv Toronto, Sunnybrook Hlth Sci Ctr, Med Outcomes & Res Econ MORE Res Grp, Toronto, ON, Canada
Abraha, Haben Y.
Lanctot, Krista L.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Toronto, Sunnybrook Hlth Sci Ctr, Med Outcomes & Res Econ MORE Res Grp, Toronto, ON, CanadaUniv Toronto, Sunnybrook Hlth Sci Ctr, Med Outcomes & Res Econ MORE Res Grp, Toronto, ON, Canada
Lanctot, Krista L.
Paes, Bosco
论文数: 0引用数: 0
h-index: 0
机构:
McMaster Univ, Dept Pediat, Div Neonatol, Hamilton, ON, CanadaUniv Toronto, Sunnybrook Hlth Sci Ctr, Med Outcomes & Res Econ MORE Res Grp, Toronto, ON, Canada
机构:
Univ Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
Fdn IRCCS Ca Granda Osped Maggiore Policlin, Adult Cyst Fibrosis Ctr, Milan, ItalyUniv Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
Aliberti, Stefano
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机构:
Reyes, Luis F.
Faverio, Paola
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milano Bicocca, AO San Gerardo, Sch Med & Surg, Monza, ItalyUniv Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
Faverio, Paola
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Sotgiu, Giovanni
Dore, Simone
论文数: 0引用数: 0
h-index: 0
机构:
Univ Sassari, Clin Epidemiol & Med Stat Unit, Dept Biomed Sci, Res Med Educ & Profess Dev Unit,AOU Sassari, Sassari, ItalyUniv Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
Dore, Simone
Rodriguez, Alejandro H.
论文数: 0引用数: 0
h-index: 0
机构:
Hosp Univ Joan XXIII, Crit Care Med, Tarragona, SpainUniv Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
Rodriguez, Alejandro H.
Soni, Nilam J.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Texas Hlth Sci Ctr San Antonio, Div Pulm Dis & Crit Care Med, San Antonio, TX 78229 USA
South Texas Vet Hlth Care Syst, Div Pulm Dis & Crit Care Med, San Antonio, TX USAUniv Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
Soni, Nilam J.
Restrepo, Marcos I.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Texas Hlth Sci Ctr San Antonio, Div Pulm Dis & Crit Care Med, San Antonio, TX 78229 USA
South Texas Vet Hlth Care Syst, Div Pulm Dis & Crit Care Med, San Antonio, TX USAUniv Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy
机构:
Univ Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, ItalyUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Aliberti, Stefano
Cilloniz, Catia
论文数: 0引用数: 0
h-index: 0
机构:
Hosp Clin Barcelona, Ciberes, IDIBAPS, Barcelona, SpainUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Cilloniz, Catia
Chalmers, James D.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Dundee, Ninewells Hosp & Med Sch, Tayside Resp Res Grp, Dundee DD1 9SY, ScotlandUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Chalmers, James D.
Zanaboni, Anna Maria
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milan, Comp Sci Dept, I-20122 Milan, ItalyUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Zanaboni, Anna Maria
Cosentini, Roberto
论文数: 0引用数: 0
h-index: 0
机构:
Osped Maggiore Policlin, Emergency Med Dept, IRCCS Fdn Ca Granda, Milan, ItalyUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Cosentini, Roberto
Tarsia, Paolo
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milan, Dept Pathophysiol & Transplantat, IRCCS Fdn Ca Granda Osped Maggiore Policlin, I-20122 Milan, ItalyUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Tarsia, Paolo
Pesci, Alberto
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, ItalyUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Pesci, Alberto
Blasi, Francesco
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milan, Dept Pathophysiol & Transplantat, IRCCS Fdn Ca Granda Osped Maggiore Policlin, I-20122 Milan, ItalyUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
Blasi, Francesco
Torres, Antoni
论文数: 0引用数: 0
h-index: 0
机构:
Hosp Clin Barcelona, Ciberes, IDIBAPS, Barcelona, SpainUniv Milano Bicocca, Dept Hlth Sci, Clin Pneumol, AO San Gerardo, Monza, Italy
机构:
Univ Milan, IRCCS Fdn Ca Granda Osped Maggiore Policlin, Dipartimento Toraco Polmonare & Cardiocircolatori, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Di Pasquale, Marta
Zanaboni, Anna Maria
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milan, Dept Comp Sci, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Zanaboni, Anna Maria
Cosentini, Roberto
论文数: 0引用数: 0
h-index: 0
机构:
Osped Maggiore Policlin, IRCCS Fdn Ca Granda, Dept Emergency Med, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Cosentini, Roberto
Brambilla, Anna Maria
论文数: 0引用数: 0
h-index: 0
机构:
Osped Maggiore Policlin, IRCCS Fdn Ca Granda, Dept Emergency Med, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Brambilla, Anna Maria
Seghezzi, Sonia
论文数: 0引用数: 0
h-index: 0
机构:
Osped Maggiore Policlin, IRCCS Fdn Ca Granda, Dept Emergency Med, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Seghezzi, Sonia
Tarsia, Paolo
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milan, IRCCS Fdn Ca Granda Osped Maggiore Policlin, Dipartimento Toraco Polmonare & Cardiocircolatori, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Tarsia, Paolo
Mantero, Marco
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy
Mantero, Marco
Blasi, Francesco
论文数: 0引用数: 0
h-index: 0
机构:
Univ Milan, IRCCS Fdn Ca Granda Osped Maggiore Policlin, Dipartimento Toraco Polmonare & Cardiocircolatori, Milan, ItalyUniv Milano Bicocca, Dipartimento Med Clin & Prevenz, Clin Pneumol, AO San Gerardo, I-20052 Monza, Italy