Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity

被引:298
作者
Wang, Xinzhou [1 ]
Zhang, Peng [2 ]
Zhang, Xin [1 ]
机构
[1] Ningbo Univ, Dept Food Sci & Engn, Ningbo 315211, Peoples R China
[2] Xinyang Normal Univ, Dept Student Affairs, Xinyang 464000, Peoples R China
关键词
gut microbiota; probiotics; immunity; ADAPTIVE IMMUNITY; SYSTEM; SLEEP; INNATE; CANCER; AXIS; SKIN; MODULATION; MECHANISMS; DISEASE;
D O I
10.3390/molecules26196076
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Probiotics are beneficial active microorganisms that colonize the human intestines and change the composition of the flora in particular parts of the host. Recently, the use of probiotics to regulate intestinal flora to improve host immunity has received widespread attention. Recent evidence has shown that probiotics play significant roles in gut microbiota composition, which can inhibit the colonization of pathogenic bacteria in the intestine, help the host build a healthy intestinal mucosa protective layer, and enhance the host immune system. Based on the close relationship between the gut microbiota and human immunity, it has become an extremely effective way to improve human immunity by regulating the gut microbiome with probiotics. In this review, we discussed the influence of probiotics on the gut microbiota and human immunity, and the relationship between immunity, probiotics, gut microbiota, and life quality. We further emphasized the regulation of gut microflora through probiotics, thereby enhancing human immunity and improving people's lives.
引用
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页数:15
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共 105 条
[1]   Mucosal immune system of the gastrointestinal tract: maintaining balance between the good and the bad [J].
Ahluwalia, Bani ;
Magnusson, Maria K. ;
Ohman, Lena .
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2017, 52 (11) :1185-1193
[2]   Human Gut Microbiome and Risk for Colorectal Cancer [J].
Ahn, Jiyoung ;
Sinha, Rashmi ;
Pei, Zhiheng ;
Dominianni, Christine ;
Wu, Jing ;
Shi, Jianxin ;
Goedert, James J. ;
Hayes, Richard B. ;
Yang, Liying .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2013, 105 (24) :1907-1911
[3]   Stress, immunity, cytokines and depression [J].
Anisman, H .
ACTA NEUROPSYCHIATRICA, 2002, 14 (06) :251-261
[4]  
Aoun Antoine, 2020, Prev Nutr Food Sci, V25, P113, DOI 10.3746/pnf.2020.25.2.113
[5]   Probiotics with ameliorating effects on the severity of skin inflammation in psoriasis: Evidence from experimental and clinical studies [J].
Atabati, Hadi ;
Esmaeili, Seyed-Alireza ;
Saburi, Ehsan ;
Akhlaghi, Maedeh ;
Raoofi, Amir ;
Rezaei, Nima ;
Momtazi-Borojeni, Amir Abbas .
JOURNAL OF CELLULAR PHYSIOLOGY, 2020, 235 (12) :8925-8937
[6]   Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice [J].
Bagarolli, Renata A. ;
Tobar, Natalia ;
Oliveira, Alexandre G. ;
Araujo, Tiago G. ;
Carvalho, Bruno M. ;
Rocha, Guilherme Z. ;
Vecina, Juliana F. ;
Calisto, Kelly ;
Guadagnini, Dioze ;
Prada, Patricia O. ;
Santos, Andrey ;
Saad, Sara T. O. ;
Saad, Mario J. A. .
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2017, 50 :16-25
[7]   FUNCTIONAL MECHANISMS OF PROBIOTICS [J].
Bajaj, Bijender Kumar ;
Claes, Ingmar J. J. ;
Lebeer, Sarah .
JOURNAL OF MICROBIOLOGY BIOTECHNOLOGY AND FOOD SCIENCES, 2015, 4 (04) :321-327
[8]   Acute sleep deprivation has no lasting effects on the human antibody titer response following a novel influenza A H1N1 virus vaccination [J].
Benedict, Christian ;
Brytting, Maria ;
Markstrom, Agneta ;
Broman, Jan-Erik ;
Schioth, Helgi Birgir .
BMC IMMUNOLOGY, 2012, 13
[9]   Sleep and immune function [J].
Besedovsky, Luciana ;
Lange, Tanja ;
Born, Jan .
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2012, 463 (01) :121-137
[10]   Gut microbiome approaches to treat obesity in humans [J].
Bianchi, Fernanda ;
Rocha Faria Duque, Ana Luiza ;
Isay Saad, Susana Marta ;
Sivieri, Katia .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2019, 103 (03) :1081-1094