Does tranexamic acid improve outcomes in traumatic brain injury?

被引:7
作者
Mahmood, Abda [1 ]
Roberts, Ian [1 ]
Shakur, Haleema [2 ]
Harris, Tim [3 ]
Belli, Antonio [4 ]
机构
[1] Univ London, London Sch Hyg & Trop Med, Clin Trials Unit, Epidemiol & Populat Hlth, London WC1E 7HU, England
[2] Univ London, London Sch Hyg & Trop Med, Clin Trials Unit, Clin Trials, London WC1E 7HU, England
[3] Barts Hlth NHS Trust, Royal London Hosp, Dept Emergency Med, Emergency Med, London, England
[4] Univ Hosp Birmingham NHS Fdn Trust, NIHR Surg Reconstruct & Microbiol Res Ctr, Trauma Neurosurg, Birmingham, W Midlands, England
来源
BMJ-BRITISH MEDICAL JOURNAL | 2016年 / 354卷
关键词
HEAD-INJURY; HEMORRHAGE; COAGULATION; PROGRESSION; ADULTS;
D O I
10.1136/bmj.i4814
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页数:7
相关论文
共 29 条
[1]   Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage [J].
Baharoglu, Merih I. ;
Germans, Menno R. ;
Rinkel, Gabriel J. E. ;
Algra, Ale ;
Vermeulen, Marinus ;
van Gijn, Jan ;
Roos, Yvo B. W. E. M. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2013, (08)
[2]   Fibrinolytic markers and neurologic outcome in traumatic brain injury [J].
Bayir, Aysegul ;
Kalkan, Erdal ;
Kocak, Sedat ;
Ak, Ahmet ;
Cander, Basar ;
Bodur, Said .
NEUROLOGY INDIA, 2006, 54 (04) :363-365
[3]   The epidemiology of traumatic brain injury: A review [J].
Bruns, TJ ;
Hauser, WA .
EPILEPSIA, 2003, 44 :2-10
[4]   THE GLOBAL BURDEN OF TRAUMATIC BRAIN INJURY: PRELIMINARY RESULTS FROM THE GLOBAL BURDEN OF DISEASE PROJECT [J].
Bryan-Hancock, C. ;
Harrison, J. .
INJURY PREVENTION, 2010, 16 :A17-A17
[5]   Traumatic brain injury may be an independent risk factor for stroke [J].
Burke, James F. ;
Stulc, Jessica L. ;
Skolarus, Lesli E. ;
Sears, Erika D. ;
Zahuranec, Darin B. ;
Morgenstern, Lewis B. .
NEUROLOGY, 2013, 81 (01) :33-39
[6]   Head injury: triage, assessment, investigation and early management of head injury in children, young people and adults (NICE guideline CG 176) [J].
Davis, Tessa ;
Ings, Anna .
ARCHIVES OF DISEASE IN CHILDHOOD-EDUCATION AND PRACTICE EDITION, 2015, 100 (02) :97-100
[7]   CRASH-3-tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial [J].
Dewan, Yashbir ;
Komolafe, Edward O. ;
Mejia-Mantilla, Jorge H. ;
Perel, Pablo ;
Roberts, Ian ;
Shakur, Haleema .
TRIALS, 2012, 13
[8]  
Edwards P, 2005, LANCET, V365, P1957
[9]   Trauma, Shock, and Disseminated Intravascular Coagulation Lessons from the Classical Literature [J].
Gando, Satoshi ;
Sawamura, Atsushi ;
Hayakawa, Mineji .
ANNALS OF SURGERY, 2011, 254 (01) :10-19
[10]   Coagulation disorders after traumatic brain injury [J].
Harhangi, B. S. ;
Kompanje, E. J. O. ;
Leebeek, F. W. G. ;
Maas, A. I. R. .
ACTA NEUROCHIRURGICA, 2008, 150 (02) :165-175