Chromo-fluorogenic detection of aldehydes with a rhodamine based sensor featuring an intramolecular deoxylactam

被引:53
作者
Li, Zhu [1 ,2 ,3 ,4 ]
Xue, Zhongwei [1 ,2 ]
Wu, Zhisheng [1 ,2 ]
Han, Jiahuai [3 ,4 ]
Han, Shoufa [1 ,2 ]
机构
[1] Xiamen Univ, Dept Chem Biol, Coll Chem & Chem Engn, Xiamen 361005, Peoples R China
[2] Xiamen Univ, Key Lab Chem Biol Fujian Prov, Xiamen 361005, Peoples R China
[3] Xiamen Univ, State Key Lab Cellular Stress Biol, Xiamen 361005, Fujian, Peoples R China
[4] Xiamen Univ, Sch Life Sci, Xiamen 361005, Fujian, Peoples R China
关键词
FORMALDEHYDE-RELEASING PRODRUGS; CELLS; REAGENT; SYSTEM; PROBE; ACID; PH; AIR;
D O I
10.1039/c1ob06448g
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A chromogenic and fluorogenic detection of aldehydes was achieved via analyte triggered opening of the deoxylactam of N-(rhodamine B)-deoxylactam-ethylenediamine (dRB-EDA). The utility of the sensor was demonstrated by fluorescent labeling of aldehyde-displaying sialoproteins on cell surfaces.
引用
收藏
页码:7652 / 7654
页数:3
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