p16INK4:: Involvement early and often in gastrointestinal malignancies

被引：20

作者：

Herman, JG ^{[1
]}

机构：

[1] Johns Hopkins Oncol Ctr, Baltimore, MD 21231 USA

来源：

GASTROENTEROLOGY | 1999年 / 116卷 / 02期

关键词：

D O I：

10.1016/S0016-5085(99)70146-0

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

引用

页码：483 / 485

页数：3

共 21 条

[1]

Barrett MT, 1996, ONCOGENE, V13, P1867

[2] Aberrant methylation of p16INK4a is an early event in lung cancer and a potential biomarker for early diagnosis [J].

Belinsky, SA ;

Nikula, KJ ;

Palmisano, WA ;

Michels, R ;

Saccomanno, G ;

Gabrielson, E ;

Baylin, SB ;

Herman, JG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (20) :11891-11896

[3] FREQUENCY OF HOMOZYGOUS DELETION AT P16/CDKN2 IN PRIMARY HUMAN TUMORS [J].

CAIRNS, P ;

POLASCIK, TJ ;

EBY, Y ;

TOKINO, K ;

CALIFANO, J ;

MERLO, A ;

MAO, L ;

HERATH, J ;

JENKINS, R ;

WESTRA, W ;

RUTTER, JL ;

BUCKLER, A ;

GABRIELSON, E ;

TOCKMAN, M ;

CHO, KR ;

HEDRICK, L ;

BOVA, GS ;

ISAACS, W ;

KOCH, W ;

SCHWAB, D ;

SIDRANSKY, D .

NATURE GENETICS, 1995, 11 (02) :210-212

[4] FREQUENT SOMATIC MUTATIONS AND HOMOZYGOUS DELETIONS OF THE P16 (MTS1) GENE IN PANCREATIC ADENOCARCINOMA [J].

CALDAS, C ;

HAHN, SA ;

DACOSTA, LT ;

REDSTON, MS ;

SCHUTTE, M ;

SEYMOUR, AB ;

WEINSTEIN, CL ;

HRUBAN, RH ;

YEO, CJ ;

KERN, SE .

NATURE GENETICS, 1994, 8 (01) :27-32

[5] Germ-line mutations of the p16(INK4)(MTS1) gene occur in a subset of patients with hepatocellular carcinoma [J].

Chaubert, P ;

Gayer, R ;

Zimmermann, A ;

Fontolliet, C ;

Stamm, B ;

Bosman, F ;

Shaw, P .

HEPATOLOGY, 1997, 25 (06) :1376-1381

[6] Inactivation of p16 in human mammary epithelial cells by CpG island methylation [J].

Foster, SA ;

Wong, DJ ;

Barrett, MT ;

Galloway, DA .

MOLECULAR AND CELLULAR BIOLOGY, 1998, 18 (04) :1793-1801

[7]

GONZALEZZULUETA M, 1995, CANCER RES, V55, P4531

[8] Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE) [J].

Gonzalgo, ML ;

Jones, PA .

NUCLEIC ACIDS RESEARCH, 1997, 25 (12) :2529-2531

[9]

HERMAN JG, 1995, CANCER RES, V55, P4525

[10] Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands [J].

Herman, JG ;

Graff, JR ;

Myohanen, S ;

Nelkin, BD ;

Baylin, SB .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (18) :9821-9826

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