Signs and Symptoms of Hypoparathyroidism

被引:31
作者
Cusano, Natalie E. [1 ]
Bilezikian, John P. [2 ]
机构
[1] Zucker Sch Med Hofstra Northwell, Dept Med, Bone Metab Program, Lenox Hill Hosp, 110 East 59th St,8th Floor,Suite 8B, New York, NY 10022 USA
[2] Columbia Univ, Dept Med, Div Endocrinol, Coll Physicians & Surg, 630 West 168th St,PH 8W-864, New York, NY 10032 USA
基金
美国国家卫生研究院;
关键词
Hypoparathyroidism; Complication; Renal failure; Basal ganglia calcification; Cataract; BASAL GANGLIA CALCIFICATION; QUALITY-OF-LIFE; IDIOPATHIC HYPOPARATHYROIDISM; POSTSURGICAL HYPOPARATHYROIDISM; FOLLOW-UP; HYPOCALCEMIA; MANIFESTATIONS; CALCIUM; MANAGEMENT; PTH(1-84);
D O I
10.1016/j.ecl.2018.07.001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hypoparathyroidism is associated with a spectrum of clinical manifestations in the acute and chronic settings, from mild to debilitating. Although the acute symptoms of hypocalcemia are primarily due to neuromuscular irritability, the chronic manifestations of hypoparathyroidism may be due to the disease itself or to complications of therapy or to both. The chronic complications of hypoparathyroidism can affect multiple organ systems, including the renal, neurologic, neuropsychiatric, skeletal, and immune systems. Further research is needed to determine the pathophysiology of complications in hypoparathyroidism and whether interventions can decrease the risk of these complications.
引用
收藏
页码:759 / +
页数:13
相关论文
共 63 条
[1]   Rare case of idiopathic hypoparathyroidism with varied neurological manifestations [J].
Abe, S ;
Tojo, K ;
Ichida, K ;
Shigematsu, T ;
Hasegawa, T ;
Morita, M ;
Sakai, O .
INTERNAL MEDICINE, 1996, 35 (02) :129-134
[2]   Neuropsychological dysfunction in idiopathic hypoparathyroidism and its relationship with intracranial calcification and serum total calcium [J].
Aggarwal, Sameer ;
Kailash, Suparna ;
Sagar, Rajesh ;
Tripathi, Manjari ;
Sreenivas, Vishnubhatla ;
Sharma, Raju ;
Gupta, Nandita ;
Goswami, Ravinder .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2013, 168 (06) :895-903
[3]   CLINICAL VARIATION OF AUTOIMMUNE POLYENDOCRINOPATHY CANDIDIASIS ECTODERMAL DYSTROPHY (APECED) IN A SERIES OF 68 PATIENTS [J].
AHONEN, P ;
MYLLARNIEMI, S ;
SIPILA, I ;
PERHEENTUPA, J .
NEW ENGLAND JOURNAL OF MEDICINE, 1990, 322 (26) :1829-1836
[4]   HYPOCALCEMIC TORSADES DE POINTES [J].
AKIYAMA, T ;
BATCHELDER, J ;
WORSMAN, J ;
MOSES, HW ;
JEDLINSKI, M .
JOURNAL OF ELECTROCARDIOLOGY, 1989, 22 (01) :89-92
[5]  
Albright F, 1941, JAMA-J AM MED ASSOC, V117, P527
[6]   CALCIUM, MAGNESIUM, AND PSYCHOTIC SYMPTOMS IN A GIRL WITH IDIOPATHIC HYPOPARATHYROIDISM [J].
ANG, AWK ;
KO, SM ;
TAN, CH .
PSYCHOSOMATIC MEDICINE, 1995, 57 (03) :299-302
[7]   Well-being, mood and calcium homeostasis in patients with hypoparathyroidism receiving standard treatment with calcium and vitamin D [J].
Arlt, W ;
Fremerey, C ;
Callies, F ;
Reincke, M ;
Schneider, P ;
Timmermann, W ;
Allolio, B .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2002, 146 (02) :215-222
[8]   HYPOCALCEMIC CARDIOMYOPATHY [J].
BASHOUR, T ;
BASHA, HS ;
CHENG, TO .
CHEST, 1980, 78 (04) :663-665
[9]   EPILEPSY AND ELECTROENCEPHALOGRAPHIC ABNORMALITIES IN CHRONIC SURGICAL HYPOPARATHYROIDISM [J].
BASSER, LS ;
NEALE, FC ;
IRELAND, AW ;
POSEN, S .
ANNALS OF INTERNAL MEDICINE, 1969, 71 (03) :507-+
[10]  
BAUMERT T, 1993, CLIN INVESTIGATOR, V71, P924