Cytotoxic constituents of the fruits of Cananga odorata

被引：75
作者：
Hsieh, TJ
Chang, FR
Chia, YC
Chen, CY
Chin, HF
Wu, YC [1 ]
机构：
[1] Kaohsiung Med Univ, Grad Inst Nat Prod, Kaohsiung 807, Taiwan
[2] Tajen Inst Technol, Dept Food Sanitat, Pingtung 907, Taiwan
[3] Fooyin Inst Technol, Dept Nursing, Kaohsiung Cty 831, Taiwan
来源：
JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 05期
关键词：
D O I：
10.1021/np0005208
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A new guaipyridine sesquiterpene alkaloid, cananodine (1), and two new eudesmane sesquiterpines, cryptomeridiol 11-alpha -L-rhamnoside (2) and gamma -eudesmol 11-alpha -L-rhamnoside (3), along with gamma -eudesmol (4), were isolated from the fruits of Cananga odorata. The structures of compounds 1-3 were established on the basis of NMR and MS methods. In addition, compounds 1-4 and four previously reported alkaloids, cleistopholine (5), N-trans-feruloyltyramine (8), (+)-ushinsunine-beta -N-oxide (7), and lyscamine (8), were evaluated for cytotoxicity against two human hepatocarcinoma cell lines.
引用
收藏
页码：616 / 619
页数：4
相关论文
共 25 条
  • [1] COMPLETE STRUCTURE OF THE POLYSACCHARIDE FROM STREPTOCOCCUS-SANGUIS J22
    ABEYGUNAWARDANA, C
    BUSH, CA
    CISAR, JO
    [J]. BIOCHEMISTRY, 1990, 29 (01) : 234 - 248
  • [2] NMR-SPECTROSCOPY IN THE STRUCTURAL ELUCIDATION OF OLIGOSACCHARIDES AND GLYCOSIDES
    AGRAWAL, PK
    [J]. PHYTOCHEMISTRY, 1992, 31 (10) : 3307 - 3330
  • [3] Sesquiterpene glycosides and phenylpropanoid esters from Phonus arborescens (Carthamus arborescens)
    Barrero, AF
    Arteaga, P
    Quilez, JF
    Rodriguez, I
    Herrador, MM
    [J]. JOURNAL OF NATURAL PRODUCTS, 1997, 60 (10): : 1026 - 1030
  • [4] STRUCTURES OF TWO ALKALOIDS FROM PATCHOULI OIL
    BUCHI, G
    GOLDMAN, IM
    MAYO, DW
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1966, 88 (13) : 3109 - &
  • [5] USE OF AN AQUEOUS SOLUBLE TETRAZOLIUM FORMAZAN ASSAY FOR CELL-GROWTH ASSAYS IN CULTURE
    CORY, AH
    OWEN, TC
    BARLTROP, JA
    CORY, JG
    [J]. CANCER COMMUNICATIONS, 1991, 3 (07): : 207 - 212
  • [6] Antiproliferative triterpene saponins from Trevesia palmata
    De Tommasi, N
    Autore, G
    Bellino, A
    Pinto, A
    Pizza, C
    Sorrentino, R
    Venturella, P
    [J]. JOURNAL OF NATURAL PRODUCTS, 2000, 63 (03): : 308 - 314
  • [7] COMPARISON OF THE NEUTRAL RED AND METHYLENE-BLUE ASSAYS TO STUDY CELL-GROWTH IN CULTURE
    ELLIOTT, WM
    AUERSPERG, N
    [J]. BIOTECHNIC & HISTOCHEMISTRY, 1993, 68 (01) : 29 - 35
  • [8] C-13 NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY OF NATURALLY-OCCURRING SUBSTANCES .74. STRUCTURE-ANALYSIS OF PROXIMADIOL (CRYPTOMERIDIOL) BY C-13 NMR-SPECTROSCOPY
    EVANS, FE
    MILLER, DW
    CAIRNS, T
    BADDELEY, GV
    WENKERT, E
    [J]. PHYTOCHEMISTRY, 1982, 21 (04) : 937 - 938
  • [9] COMPOSITION OF THE ESSENTIAL OIL OF YLANG-YLANG (CANANGA-ODORATA HOOK FIL ET THOMSON FORMA-GENUINA) FROM MADAGASCAR
    GAYDOU, EM
    RANDRIAMIHARISOA, R
    BIANCHINI, JP
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1986, 34 (03) : 481 - 487
  • [10] The constituents of Cananga odorata
    Hsieh, TJ
    Chang, FR
    Wu, YC
    [J]. JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1999, 46 (04) : 607 - 611
123