The Use of Hydroxyurea in the Treatment of COVID-19

被引:6
作者
Foster, Melissa Robin Bowman [1 ]
Hijazi, Ali Atef [1 ]
Opoku, Rebecca [1 ]
Varghese, Priya [1 ]
Li, Chun [1 ]
机构
[1] Winston Salem State Univ, Winston Salem, NC 27110 USA
关键词
COVID-19; treatment; hydroxyurea; critical respiratory care;
D O I
10.2478/jccm-2021-0019
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Introduction: The rapid worldwide spread of COVID-19 motivated medical professionals to pursue and authenticate appropriate remedies and treatment protocols. This article aims to analyze the potential benefits of one treatment protocol developed by a group of care providers caring for severe COVID-19 patients. Methods: The clinical findings of COVID-19 patients who were transferred to a specialized care hospital after unsuccessful treatment in previous institutions, were analyzed. The specialized care hospital used a treatment protocol including hydroxyurea, a medication commonly used for sickle cell treatment, to improve respiratory distress in the COVID-19 patients. None of the COVID-19 patients included in the analyzed data were diagnosed with sickle cell, and none had previously taken hydroxyurea for any other conditions. Results: In all presented cases, patients reverted to their baseline respiratory health after treatment with the hydroxyurea protocol. There was no significant difference in the correlation between COVID-19 and hydroxyurea. However, deaths were extremely low for those taking hydroxyurea. Conclusions: Fatalnumbers were low for those death could be attributed to other issues.
引用
收藏
页码:312 / 317
页数:6
相关论文
共 50 条
  • [1] Will the Use of Pharmacogenetics Improve Treatment Efficiency in COVID-19?
    Franczyk, Beata
    Rysz, Jacek
    Milonski, Jaroslaw
    Konecki, Tomasz
    Rysz-Gorzynska, Magdalena
    Gluba-Brzozka, Anna
    PHARMACEUTICALS, 2022, 15 (06)
  • [2] The use of Hydroxychloroquine in the Treatment of COVID-19
    Tecen-Yucel, Kamer
    Kara, Emre
    Demirkan, Kutay
    Unal, Serhat
    FLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI, 2020, 25 (03): : 283 - 291
  • [3] Repurposing of Hydroxyurea Against COVID-19: A Promising Immunomodulatory Role
    Ben Moftah, Moayed
    Eswayah, Asma
    ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES, 2022, 20 (01) : 55 - 62
  • [4] Favipiravir Use in COVID-19 Treatment
    Kara, Emre
    Inkaya, Ahmet Cagkan
    Demirkan, Kutay
    Unal, Serhat
    FLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI, 2021, 26 (01): : 1 - 11
  • [5] Use of Casirivimab and Imdevimab for the Treatment of COVID-19
    Liu, Ryan
    Mangal, Rohan
    Stead, Thor S.
    Barbera, Andrew R.
    Ganti, Latha
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2022, 14 (08)
  • [6] Optimizing the use of vilobelimab for the treatment of COVID-19
    McCarthy, Matthew W.
    EXPERT OPINION ON BIOLOGICAL THERAPY, 2023, 23 (09) : 877 - 881
  • [7] Peptides: Prospects for Use in the Treatment of COVID-19
    Khavinson, Vladimir
    Linkova, Natalia
    Dyatlova, Anastasiia
    Kuznik, Boris
    Umnov, Roman
    MOLECULES, 2020, 25 (19):
  • [8] Review the Use of Antivirus for COVID-19 Treatment
    Prayitno, Lukman
    Mawuntu, Julien Rosye
    Herna
    Angkasawati, Tri Juni
    JOURNAL OF HEALTH MANAGEMENT, 2020, 22 (04) : 578 - 592
  • [9] The use of Ephedra herbs in the treatment of COVID-19
    Dousari, Amin Sadeghi
    Amroabadi, Marzieh Karimian
    Neyestani, Zahra Soofi
    Moghadam, Majid Taati
    Satarzadeh, Naghmeh
    AVICENNA JOURNAL OF PHYTOMEDICINE, 2023, 13 (03) : 231 - 239
  • [10] Treatment of Acute COVID-19 and COVID-19 Exposures in Children and Adolescents
    Daniels, Danielle
    Conners, Gregory P.
    PEDIATRIC EMERGENCY CARE, 2024, 40 (03) : 223 - 230