Triterpenoids and Diterpenoids from Viburnum chingii

被引：18

作者：

Chen, Xuan-Qin ^{[1
,2
,3
]}

Li, Yan ^{[1
]}

He, Juan ^{[1
]}

Cheng, Xiao ^{[1
]}

Wang, Kou ^{[1
,3
]}

Li, Ming-Ming ^{[1
,3
]}

Pan, Zheng-Hong ^{[1
,3
]}

Peng, Li-Yan ^{[1
]}

Zhao, Qin-Shi ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China

[2] Kunming Univ Sci & Technol, Life Sci & Technol Sch, Biotechnol Res Ctr, Kunming 650224, Yunnan, Peoples R China

[3] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2011年 / 59卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Viburnum chingii; oleanane triterpenoid; vibsane diterpenoid; OLEANANE-TYPE TRITERPENES; AWABUKI; SPECTROMETRY; CONSTITUENTS; ASSAY;

D O I：

10.1248/cpb.59.496

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new oleanane triterpenoids (1-2) and one new vibsane-type diterpenoid (3), together with 7 known compounds (4-10), were isolated from the leaves of Viburnum chingii. The structures of compounds 1-3 were elucidated by means of spectroscopic methods including extensive 1D- and 2D-NMR technique. Cytotoxicity of compounds 1-10 were tested against HL-60, SMMC-7721, A-549, SK-BR-3, and PANC-1 cell lines. Compound 3 showed significant cytotoxicity against HL-60, SK-BR-3, and PANC-1 cell lines.

引用

页码：496 / 498

页数：3

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