Rhodium-Catalyzed Synthesis of 2,3-Disubstituted Indoles from α,β-Disubstituted Stryryl Azides

被引：128
作者：
Sun, Ke [1 ]
Liu, Sheng [1 ]
Bec, Patryk M. [1 ]
Driver, Tom G. [1 ]
机构：
[1] Univ Illinois, Dept Chem, 845 W Taylor St, Chicago, IL 60607 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 07期
基金：
美国国家卫生研究院;
关键词：
1,2-shift; azides; indoles; nitrenes; rhodium complexes; C-H AMINATION; ARYL AZIDES; CASCADE REACTIONS; NITROGEN-SOURCES; ORGANIC AZIDES; PHENONIUM ION; COMPLEXES; AZIRIDINATION; COPPER; FUNCTIONALIZATION;
D O I：
10.1002/anie.201006917
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Rings la carte: Rhodium carboxylate complexes catalyze selective cascade reactions to produce a range 2,3-disubstituted indoles from β,β- disubstituted stryryl azides. The selective migration of aryl groups appears to originate from a putative phenonium ion reactive intermediate (see scheme). © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：1702 / 1706
页数：5
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