DNA Nanocages

被引：79
作者：
Chandrasekaran, Arun Richard [1 ]
Levchenko, Oksana [1 ]
机构：
[1] SUNY Albany, RNA Inst, Albany, NY 12222 USA
来源：
CHEMISTRY OF MATERIALS | 2016年 / 28卷 / 16期
关键词：
ORIGAMI NANOSTRUCTURES; STRUCTURAL-ANALYSIS; SINGLE; COMPLEX; NANOPARTICLES; ENCAPSULATION; TETRAHEDRON; ARRAYS; CONSTRUCTION; MOLECULE;
D O I：
10.1021/acs.chemmater.6b02546
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
DNA has been used in the construction of a variety of nanoscale structures. Of these, designed cage-like structures of sizes ranging from similar to 10 to similar to 100 nm and molecular weights of up to similar to 60 MDa have been. developed. These nanocages have been assembled using different strategies that include a one-pot approach, modular assembly, hierarchical self assembly, and the DNA origami technique. Such structures can be programmed to be reconfigurable via external triggers such as ligands, biomolecules, and pH. These objects provide a route to encapsulate proteins and nanoparticles and allow targeted delivery of these guests. With such versatile properties, DNA nanocages find applications in medicine, biotechnology, imaging, and materials science.
引用
收藏
页码：5569 / 5581
页数：13
相关论文
共 117 条
[31]   Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication [J].
Goodman, RP ;
Schaap, IAT ;
Tardin, CF ;
Erben, CM ;
Berry, RM ;
Schmidt, CF ;
Turberfield, AJ .
SCIENCE, 2005, 310 (5754) :1661-1665
[32]   Reconfigurable, braced, three-dimensional DNA nanostructures [J].
Goodman, Russell P. ;
Heilemann, Mike ;
Doose, Soeren ;
Erben, Christoph M. ;
Kapanidis, Achillefs N. ;
Turberfield, Andrew J. .
NATURE NANOTECHNOLOGY, 2008, 3 (02) :93-96
[33]  
Guo PX, 2010, NAT NANOTECHNOL, V5, P833, DOI [10.1038/nnano.2010.231, 10.1038/NNANO.2010.231]
[34]   DNA Gridiron Nanostructures Based on Four-Arm Junctions [J].
Han, Dongran ;
Pal, Suchetan ;
Yang, Yang ;
Jiang, Shuoxing ;
Nangreave, Jeanette ;
Liu, Yan ;
Yan, Hao .
SCIENCE, 2013, 339 (6126) :1412-1415
[35]   DNA Origami with Complex Curvatures in Three-Dimensional Space [J].
Han, Dongran ;
Pal, Suchetan ;
Nangreave, Jeanette ;
Deng, Zhengtao ;
Liu, Yan ;
Yan, Hao .
SCIENCE, 2011, 332 (6027) :342-346
[36]   Construction of RNA nanocages by re-engineering the packaging RNA of Phi29 bacteriophage [J].
Hao, Chenhui ;
Li, Xiang ;
Tian, Cheng ;
Jiang, Wen ;
Wang, Guansong ;
Mao, Chengde .
NATURE COMMUNICATIONS, 2014, 5
[37]   Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra [J].
He, Yu ;
Ye, Tao ;
Su, Min ;
Zhang, Chuan ;
Ribbe, Alexander E. ;
Jiang, Wen ;
Mao, Chengde .
NATURE, 2008, 452 (7184) :198-U41
[38]   On the Chirality of Self-Assembled DNA Octahedra [J].
He, Yu ;
Su, Min ;
Fang, Ping-an ;
Zhang, Chuan ;
Ribbe, Alexander E. ;
Jiang, Wen ;
Mao, Chengde .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (04) :748-751
[39]   Shape-Controlled Synthesis of Gold Nanostructures Using DNA Origami Molds [J].
Helmi, Seham ;
Ziegler, Christoph ;
Kauert, Dominik J. ;
Seidel, Ralf .
NANO LETTERS, 2014, 14 (11) :6693-6698
[40]   Comparative simulative analysis of single and double stranded truncated octahedral DNA nanocages [J].
Iacovelli, Federico ;
Falconi, Mattia ;
Knudsen, Birgitta R. ;
Desideri, Alessandro .
RSC ADVANCES, 2016, 6 (42) :35160-35166
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