Variation in the KAP6-1 gene in Chinese Tan sheep and associations with variation in wool traits

被引：23

作者：

Tao, Jinzhong ^{[1
,2
]}

Zhou, Huitong ^{[2
,3
]}

Gong, Hua ^{[2
,3
]}

Yang, Zuoqing ^{[1
]}

Ma, Qing ^{[4
]}

Cheng, Long ^{[5
]}

Ding, Wei ^{[4
]}

Li, Yingkang ^{[4
]}

Hickford, Jon G. H. ^{[2
,3
]}

机构：

[1] Ningxia Univ, Agr Coll, Yinchuan 750021, Peoples R China

[2] Gansu Agr Univ, Int Wool Res Inst, Lanzhou 730070, Gansu, Peoples R China

[3] Lincoln Univ, Fac Agr & Life Sci, Gene Marker Lab, Lincoln 7647, New Zealand

[4] Ningxia Agr & Forestry Acad, Anim Sci Inst, Yinchuan 750002, Peoples R China

[5] Univ Melbourne, Fac Vet & Agr Sci, Dookie Campus, Victoria 3647, Australia

来源：

SMALL RUMINANT RESEARCH | 2017年 / 154卷

关键词：

Chinese Tan sheep; Crimp; KAP6-1 gene (KRTAP6-1); Variation; Wool traits; KAP8-2; GENE; FAMILY; RICH; DNA;

D O I：

10.1016/j.smallrumres.2017.08.001

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

The keratin-associated protein KAP6-1 gene (KRTAP6-1) was investigated for its effect on wool traits in Chinese Tan sheep. Two previously identified KRTAP6-1 variants (A and B) and two newly identified KRTAP6-1 variants (D and E) were detected with frequencies of 28.9%, 57.1%, 10.3% and 3.7% for A, B, D and E, respectively. The KRTAP6-1 variant C, was not found in the Chinese Tan sheep. Variant D was found to be associated with increased straightened fibre-length at birth, while variant E was found to be associated with increased straightened fibre-length, the number of crimps and the degree of crimping at approximately 35 days postpartum (conventionally called "Er-mao''). Variant E was also associated with increased wool fibre growth rate from birth to Er-mao. These results suggest that variation in ovine KRTAP6-1 may affect wool" traits in early life in Chinese Tan sheep.

引用

页码：129 / 132

页数：4

共 16 条

[1] An effective method for silver-staining DNA in large numbers of polyacrylamide gels [J].

Byun, S. O. ;

Fang, Q. ;

Zhou, H. ;

Hickford, J. G. H. .

ANALYTICAL BIOCHEMISTRY, 2009, 385 (01) :174-175

[2]

Gillespie J.M., 1990, CELLULAR MOL BIOL IN, P95

[3] RELATION BETWEEN TYROSINE CONTENT OF VARIOUS WOOLS AND THEIR CONTENT OF A CLASS OF PROTEINS RICH IN TYROSINE AND GLYCINE [J].

GILLESPIE, JM ;

DARSKUS, RL .

AUSTRALIAN JOURNAL OF BIOLOGICAL SCIENCES, 1971, 24 (06) :1189-+

[4] Wool Keratin-Associated Protein Genes in Sheep-A Review [J].

Gong, Hua ;

Zhou, Huitong ;

Forrest, Rachel H. J. ;

Li, Shaobin ;

Wang, Jiqing ;

Dyer, Jolon M. ;

Luo, Yuzhu ;

Hickford, Jon G. H. .

GENES, 2016, 7 (06)

[5] The sheep KAP8-2 gene, a new KAP8 family member that is absent in humans [J].

Gong, Hua ;

Zhou, Huitong ;

Dyer, Jolon M. ;

Hickford, Jon G. H. .

SPRINGERPLUS, 2014, 3

[6] An Updated Nomenclature for Keratin-Associated Proteins (KAPs) [J].

Gong, Hua ;

Zhou, Huitong ;

McKenzie, Grant W. ;

Yu, Zhidong ;

Clerens, Stefan ;

Dyer, Jolon M. ;

Plowman, Jeffrey E. ;

Wright, Mathew W. ;

Arora, Reena ;

Bawden, C. Simon ;

Chen, Yulin ;

Li, Jinquan ;

Hickford, Jonathan G. H. .

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2012, 8 (02) :258-264

[7] Diversity of the glycine/tyrosine-rich keratin-associated protein 6 gene (KAP6) family in sheep [J].

Gong, Hua ;

Zhou, Huitong ;

Hickford, Jon G. H. .

MOLECULAR BIOLOGY REPORTS, 2011, 38 (01) :31-35

[8] Characterization of the structural and molecular defects in fibres and follicles of the merino felting lustre mutant [J].

Li, Shu Wei ;

Ouyang, Hong Sheng ;

Rogers, George Ernest ;

Bawden, Christopher Simon .

EXPERIMENTAL DERMATOLOGY, 2009, 18 (02) :134-142

[9]

Powell B C, 1997, EXS, V78, P59

[10] Biology of the wool follicle: an excursion into a unique tissue interaction system waiting to be re-discovered [J].

Rogers, George E. .

EXPERIMENTAL DERMATOLOGY, 2006, 15 (12) :931-949

← 1 2 →