The effect of medical and operative birth interventions on child health outcomes in the first 28 days and up to 5 years of age: A linked data population-based cohort study

被引：73

作者：

Peters, Lilian L. ^{[1
,2
,3
]}

Thornton, Charlene ^{[4
]}

de Jonge, Ank ^{[1
,3
]}

Khashan, Ali ^{[5
,6
]}

Tracy, Mark ^{[7
]}

Downe, Soo ^{[8
]}

Feijen-de Jong, Esther I. ^{[1
,2
,3
]}

Dahlen, Hannah G. ^{[9
,10
,11
]}

机构：

[1] Vrije Univ Amsterdam, Amsterdam Publ Hlth Res Inst, Dept Midwifery Sci, Med Ctr Amsterdam, Amsterdam, Netherlands

[2] Univ Groningen, Univ Med Ctr Groningen, Dept Gen Practice & Elderly Care Med, Groningen, Netherlands

[3] AVAG Midwifery Acad Amsterdam Groningen, Amsterdam, Netherlands

[4] Flinders Univ S Australia, Coll Nursing & Hlth Sci Adelaide, Adelaide, SA, Australia

[5] Univ Coll Cork, Sch Publ Hlth, Cork, Ireland

[6] Univ Coll Cork INFANT, Irish Ctr Fetal & Neonatal Translat Res, Cork, Ireland

[7] Univ Sydney, Westmead Newborn Intens Care Unit, Westmead Hosp, Sydney, NSW, Australia

[8] Univ Cent Lancashire, Preston, Lancs, England

[9] Western Sydney Univ, Sch Nursing & Midwifery Sydney, Sydney, NSW, Australia

[10] Ingham Inst, Liverpool, NSW, Australia

[11] Western Sydney Univ Sydney, Natl Inst Complementary Med, Sydney, NSW, Australia

来源：

BIRTH-ISSUES IN PERINATAL CARE | 2018年 / 45卷 / 04期

关键词：

birth interventions; child's health; epidemiology; CESAREAN-SECTION; RISK; DELIVERY; ASTHMA; LABOR; MODE; METHYLATION; HYPOTHESIS; INDUCTION; PREGNANCY;

D O I：

10.1111/birt.12348

中图分类号：

R47 [护理学];

学科分类号：

1011 ;

摘要：

Background Spontaneous vaginal birth rates are decreasing worldwide, while cesarean delivery, instrumental births, and medical birth interventions are increasing. Emerging evidence suggests that birth interventions may have an effect on children's health. Therefore, the aim of our study was to examine the association between operative and medical birth interventions on the child's health during the first 28 days and up to 5 years of age. Methods Results In New South Wales (Australia), population-linked data sets were analyzed, including data on maternal characteristics, child characteristics, mode of birth, interventions during labor and birth, and adverse health outcomes of the children (ie, jaundice, feeding problems, hypothermia, asthma, respiratory infections, gastrointestinal disorders, other infections, metabolic disorder, and eczema) registered with the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, Australian Modification codes. Logistic regression analyses were performed for each adverse health outcome. Our analyses included 491 590 women and their children; of those 38% experienced a spontaneous vaginal birth. Infants who experienced an instrumental birth after induction or augmentation had the highest risk of jaundice, adjusted odds ratio (aOR) 2.75 (95% confidence interval [CI] 2.61-2.91) compared with spontaneous vaginal birth. Children born by cesarean delivery were particularly at statistically significantly increased risk for infections, eczema, and metabolic disorder, compared with spontaneous vaginal birth. Children born by emergency cesarean delivery showed the highest association for metabolic disorder, aOR 2.63 (95% CI 2.26-3.07). Conclusion Children born by spontaneous vaginal birth had fewer short- and longer-term health problems, compared with those born after birth interventions.

引用

页码：347 / 357

页数：11

共 41 条

[1] Cesarean delivery and hematopoietic stem cell epigenetics in the newborn infant: implications for future health? [J].