Synthesis and Biological Properties of Coumarin Derivatives. A Review

被引：66
作者：
Bouhaoui, Abderrazzak [1 ]
Eddahmi, Mohammed [1 ]
Dib, Mustapha [1 ]
Khouili, Mostafa [1 ]
Aires, Alfredo [2 ]
Catto, Marco [3 ]
Bouissane, Latifa [1 ]
机构：
[1] Sultan Moulay Slimane Univ, Organ & Analyt Chem Lab, Fac Sci & Technol, BP 523, Beni Mellal 23000, Morocco
[2] Univ Tras Os Montes & Alto Douro, UTAD, CITAB, Ctr Res & Technol Agroenvironm & Biol Sci, Vila Real, Portugal
[3] Univ Bari Aldo Moro, Dept Pharm Pharmaceut Sci, Via E Orabona 4, I-70125 Bari, Italy
来源：
CHEMISTRYSELECT | 2021年 / 6卷 / 24期
关键词：
ONE-POT SYNTHESIS; SOLVENT-FREE SYNTHESIS; MONOAMINE-OXIDASE-B; KNOEVENAGEL CONDENSATION; FUNCTIONALIZED COUMARIN; ASSISTED SYNTHESIS; EFFICIENT APPROACH; MOLECULAR DOCKING; ANTICANCER AGENTS; PECHMANN REACTION;
D O I：
10.1002/slct.202101346
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Coumarin and its derivatives are widely used as scaffolds in the synthesis of new heterocyclic systems. This review focuses on current developments in the synthesis of heterocyclic coumarin compounds. Numerous approaches especially involving nanoparticle catalysts have been developed to get new bioactive coumarin derivatives endowed with pharmacological and biological activities. The present work describes the reactivity and the new strategies using various catalysts for the synthesis of coumarin and its derivatives reported in the literature and their biological properties.
引用
收藏
页码：5848 / 5870
页数：23
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