Paxillin and focal adhesion signalling

被引：667

作者：

Turner, CE ^{[1
]}

机构：

[1] SUNY Upstate Med Univ, Dept Cell & Dev Biol, Syracuse, NY 13210 USA

来源：

NATURE CELL BIOLOGY | 2000年 / 2卷 / 12期

关键词：

D O I：

10.1038/35046659

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

To facilitate a rapid response to environmental change, cells use scaffolding - or adaptor - proteins to recruit key components of their signal-transduction machinery to specific subcellular locations. Paxillin is a multi-domain adaptor found at the interface between the plasma membrane and the actin cytoskeleton. Here it provides a platform for the integration and processing of adhesion- and growth factor-related signals.

引用

页码：E231 / E236

页数：6

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