Three new triterpene saponins from the seeds of Aesculus chinensis

被引：20

作者：

Zhao, J

Yang, XW ^{[1
]}

Hattori, M

机构：

[1] Beijing Univ, Natl Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China

[2] Toyama Med & Pharmaceut Univ, Inst Nat Med, Toyama 9300194, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2001年 / 49卷 / 05期

关键词：

Aesculus chinensis; Hippocastanaceae; escin IVg; escin IVh; escin Vlb;

D O I：

10.1248/cpb.49.626

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three new triterpenoid saponins were isolated from the seeds of Aesculus chinensis, and characterized as 22-tigloylprotoaescigenin 3-O-[beta -D-glucopyranosyl (1 -->2)] [beta -D-glucopyranosyl (1 -->4)]-beta -D-glucopyranosiduronic acid (escin IVg, 1), 22-angeloylprotoaescigenin 3-O-[beta -D-glucopyranosyl (1 -->2)] [beta -D-glucopyranosyl (1 -->)]-beta -D-glucopy ranosiduronic acid (escin IVh, 2) and 16-angeloyl-21-acetylprotoaescigenin 3-O-[beta -D-glucopyranosyl (1 -->2)] [beta -D-glucopyranosyl (1 -->4)]-beta -D-glucopyranosiduronic acid (escin VIb, 3), together with two known compounds, escin IIIa (4) and desacylescin I (5), Their structures H ere established on the basis of spectroscopic and chemical evidence.

引用

页码：626 / 628

页数：3

共 5 条

[1] AESCULUSIDE-B, A NEW TRITERPENE GLYCOSIDE FROM AESCULUS-INDICA [J].

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[2] Anti-HIV-1 protease triterpenoid saponins from the seeds of Aesculus chinensis [J].

Yang, XW ;

Zhao, J ;

Cui, YX ;

Liu, XH ;

Ma, CM ;

Hattori, M ;

Zhang, LH .

JOURNAL OF NATURAL PRODUCTS, 1999, 62 (11) :1510-1513

[3]

Yoshikawa M, 1996, CHEM PHARM BULL, V44, P1454, DOI 10.1248/cpb.44.1454

[4]

Zhang ZZ, 1999, CHEM PHARM BULL, V47, P1515, DOI 10.1248/cpb.47.1515

[5]

ZHOU MZ, 1996, CHINESE NEW DRUGS J, V5, P438

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