Platelet interactions with viruses and parasites

被引：25

作者：

Alonso, Ana Lopez ^{[1
]}

Cox, Dermot ^{[1
]}

机构：

[1] Royal Coll Surgeons Ireland, Mol & Cellular Therapeut, Dublin 2, Ireland

来源：

PLATELETS | 2015年 / 26卷 / 04期

关键词：

Fungi; parasites; platelets; viruses; VON-WILLEBRAND-FACTOR; FC-GAMMA-RIIA; TOLL-LIKE RECEPTOR; FALCIPARUM-INFECTED ERYTHROCYTES; BODY-DEPENDENT ENHANCEMENT; ACUTE CHAGAS-DISEASE; STAPHYLOCOCCUS-AUREUS; CEREBRAL MALARIA; IN-VITRO; DC-SIGN;

D O I：

10.3109/09537104.2015.1025376

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

While the interactions between Gram-positive bacteria and platelets have been well characterized, there is a paucity of data on the interaction between other pathogens and platelets. However, thrombocytopenia is a common feature with many infections especially viral hemorrhagic fever. The little available data on these interactions indicate a similarity with bacteria-platelet interactions with receptors such as Fc gamma RIIa and Toll-Like Receptors (TLR) playing key roles with many pathogens. This review summarizes the known interactions between platelets and pathogens such as viruses, fungi and parasites.

引用

页码：317 / 323

页数：7

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