Drug Delivery Applications with Ethosomes

被引：99
作者：
Ainbinder, D. [1 ]
Paolino, D. [2 ]
Fresta, M. [3 ]
Touitou, E. [1 ]
机构：
[1] Hebrew Univ Jerusalem, Fac Med, Sch Pharm, Inst Drug Res, IL-91120 Jerusalem, Israel
[2] Magna Graecia Univ Catanzaro, Dept Expt & Clin Med, Fac Med, I-88100 Germaneto, CZ, Italy
[3] Magna Graecia Univ Catanzaro, Fac Pharm, Dept Pharmacobiol Sci, I-88100 Germaneto, CZ, Italy
来源：
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY | 2010年 / 6卷 / 05期
关键词：
Transdermal; Dermal; Skin; Ethosome; Lipid Carrier; Nanovesicle; LASER-SCANNING MICROSCOPY; TRANSDERMAL DELIVERY; HUMAN SKIN; IN-VITRO; LIPOSOMES; VESICLES; CARRIER; VIVO; PENETRATION; PERMEATION;
D O I：
10.1166/jbn.2010.1152
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Ethosomes are specially tailored vesicular carriers able to efficiently deliver various molecules with different physicochemical properties into deep skin layers and across the skin. This paper reviews the unique characteristics of the ethosomal carriers, focusing on work carried out with drug containing ethosomal systems in animal models and in clinical studies. The paper concludes with a discussion on the safety of the ethosomal system applications.
引用
收藏
页码：558 / 568
页数：11
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