Effects of stimulant medication on divergent and convergent thinking tasks related to creativity in adults with attention-deficit hyperactivity disorder

被引:3
作者
McBride, Molly [1 ]
Appling, Carrina [2 ]
Ferguson, Bradley [2 ,3 ,4 ]
Gonzalez, Alyssia [5 ]
Schaeffer, Andrea [1 ]
Zand, Amanda [1 ]
Wang, David [6 ]
Sam, Alinna [1 ]
Hart, Eric [4 ]
Tosh, Aneesh [7 ]
Fontcha, Ivan [8 ]
Parmacek, Sophia [9 ]
Beversdorf, David [1 ,2 ,3 ,4 ,10 ,11 ,12 ]
机构
[1] Univ Missouri, Sch Med, Columbia, MO 65211 USA
[2] Univ Missouri, Interdisciplinary Neurosci Program, Columbia, MO 65211 USA
[3] Univ Missouri, Thompson Ctr Autism & Neurodev Disorder, Columbia, MO 65211 USA
[4] Univ Missouri, Dept Hlth Psychol, Columbia, MO 65211 USA
[5] Calif State Univ San Marcos, San Marcos, CA USA
[6] Emory Univ, Sch Med, Atlanta, GA USA
[7] Univ Missouri, Dept Child Hlth, Columbia, MO USA
[8] Univ Missouri, Dept Biol Sci, Columbia, MO USA
[9] Univ Missouri, Dept Psychol Sci, Columbia, MO USA
[10] Univ Missouri, Dept Radiol, Columbia, MO 65211 USA
[11] Univ Missouri, Dept Neurol, Columbia, MO 65211 USA
[12] Univ Missouri, Dept Psychol Sci, Columbia, MO 65211 USA
基金
美国国家科学基金会;
关键词
Stimulant medication; Attention-deficit hyperactivity disorder; Creativity; Dopamine; Norepinephrine; DEFICIT/HYPERACTIVITY DISORDER; INTEGRATIVE THEORY; ADHD; METHYLPHENIDATE; FLEXIBILITY; MODULATION; MECHANISMS; GENERATION; COGNITION; IDEA;
D O I
10.1007/s00213-021-05970-0
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Rationale Common pharmacological treatments for attention-deficit hyperactivity disorder (ADHD) are central nervous system stimulants acting as norepinephrine-dopamine reuptake inhibitors. The noradrenergic and dopaminergic systems have been shown to impact performance on tasks assessing creativity. Some previous studies suggest higher performance on creativity tasks in ADHD. Stimulant medication has been shown to differentially impact creativity in those without ADHD. However, the full range of effects of stimulant medication on creativity in those with ADHD is not known. Objectives This study examined the effects of stimulants on convergent and divergent tasks associated with creativity in adults with ADHD. Method Seventeen adults diagnosed with ADHD who were prescribed stimulant medication attended two counterbalanced sessions: one after taking their prescribed stimulant dose and one after the dose was withheld. Participants completed convergent problem-solving (anagrams, Compound Remote Associates) and divergent generative (letter/semantic fluency, Torrance Test for Creative Thinking (TTCT)-Verbal) tasks. Results There was a significant increase in words generated on the semantic fluency task for the stimulant session. Additionally, significant increases were found in the stimulant session for originality, flexibility, and fluency scores on the TTCT. Stimulant medication did not have an effect on any of the problem-solving tasks. Conclusions Stimulant medication enhanced verbal fluency in adults with ADHD but had no effect on convergent abilities. Furthermore, stimulants enhanced fluency, flexibility, and originality scores on the TTCT. Therefore, stimulants appear to have positive effects on divergent task performance in adults with ADHD, but not convergent tasks. This finding warrants further studies into the specific roles of norepinephrine and dopamine in this effect.
引用
收藏
页码:3533 / 3541
页数:9
相关论文
共 57 条
  • [31] Annual Research Review: Reaction time variability in ADHD and autism spectrum disorders: measurement and mechanisms of a proposed trans-diagnostic phenotype
    Karalunas, Sarah L.
    Geurts, Hilde M.
    Konrad, Kerstin
    Bender, Stephan
    Nigg, Joel T.
    [J]. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY, 2014, 55 (06) : 685 - 710
  • [32] The female side of pharmacotherapy for ADHD-A systematic literature review
    Kok, Francien M.
    Groen, Yvonne
    Fuermaier, Anselm B. M.
    Tucha, Oliver
    [J]. PLOS ONE, 2020, 15 (09):
  • [33] Reports of Perceived Adverse Events of Stimulant Medication on Cognition, Motivation, and Mood: Qualitative Investigation and the Generation of Items for the Medication and Cognition Rating Scale
    Kovshoff, Hanna
    Banaschewski, Tobias
    Buitelaar, Jan K.
    Carucci, Sara
    Coghill, David
    Danckaerts, Marina
    Dittmann, Ralf W.
    Falissard, Bruno
    Grimshaw, Dina Gojkovic
    Hollis, Chris
    Inglis, Sarah
    Konrad, Kerstin
    Liddle, Elizabeth
    McCarthy, Suzanne
    Nagy, Peter
    Thompson, Margaret
    Wong, Ian C. K.
    Zuddas, Alessandro
    Sonuga-Barke, Edmund J. S.
    [J]. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 2016, 26 (06) : 537 - 547
  • [34] Krause Johanna, 2008, Expert Rev Neurother, V8, P611, DOI 10.1586/14737175.8.4.611
  • [35] An international qualitative study of ability and disability in ADHD using the WHO-ICF framework
    Mahdi, Soheil
    Viljoen, Marisa
    Massuti, Rafael
    Selb, Melissa
    Almodayfer, Omar
    Karande, Sunil
    de Vries, Petrus J.
    Rohde, Luis
    Bolte, Sven
    [J]. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, 2017, 26 (10) : 1219 - 1231
  • [36] An integrative theory of attention-deficit/hyperactivity disorder based on the cognitive and affective neurosciences
    Nigg, JT
    Casey, BJ
    [J]. DEVELOPMENT AND PSYCHOPATHOLOGY, 2005, 17 (03) : 785 - 806
  • [37] Trends in use of prescription stimulants in the United States and Territories, 2006 to 2016
    Piper, Brian J.
    Ogden, Christy L.
    Simoyan, Olapeju M.
    Chung, Daniel Y.
    Caggiano, James F.
    Nichols, Stephanie D.
    McCall, Kenneth L.
    [J]. PLOS ONE, 2018, 13 (11):
  • [38] Measuring self-perceptions of creative identity: a cross-cultural comparison of the creative identities of pre-service music teachers in the US and Australia
    Randles, Clint
    Ballantyne, Julie
    [J]. MUSIC EDUCATION RESEARCH, 2018, 20 (02) : 231 - 241
  • [39] Happy creativity: Listening to happy music facilitates divergent thinking
    Ritter, Simone M.
    Ferguson, Sam
    [J]. PLOS ONE, 2017, 12 (09):
  • [40] A dynamic developmental theory of attention-deficit/hyperactivity disorder (ADHD) predominantly hyperactive/impulsive and combined subtypes
    Sagvolden, T
    Johansen, EB
    Aase, H
    Russell, VA
    [J]. BEHAVIORAL AND BRAIN SCIENCES, 2005, 28 (03) : 397 - +