Oxygen and Water Plasma-Immersion Ion Implantation of Copper into Titanium for Antibacterial Surfaces of Medical Implants

被引:20
作者
Polak, Martin [1 ]
Ohl, Andreas [1 ]
Quaas, Marion [1 ,2 ]
Lukowski, Gerold [3 ]
Luethen, Frank [4 ]
Weltmann, Klaus-Dieter [1 ]
Schroeder, Karsten [1 ]
机构
[1] Leibniz Inst Plasma Sci & Technol, D-17489 Greifswald, Germany
[2] Ernst Moritz Arndt Univ Greifswald, Dept Phys, D-17489 Greifswald, Germany
[3] Inst Marine Biotechnol, D-17489 Greifswald, Germany
[4] Univ Rostock, Fac Med, Cell Biol Lab, D-18057 Rostock, Germany
关键词
FILMS; ANTIBIOTICS; TECHNOLOGY; REDUCTION; RELEASE;
D O I
10.1002/adem.200980048
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Plasma-immersion ion implantation (PIII) is used for the insertion of copper into titanium and its alloys to impart antimicrobial properties. Physicochemical changes inside the subsurface of titanium are investigated after PIII with either oxygen or water vapor. O-2-Cu-PIII produces copper oxides inside the surface of the titanium oxide; H2O-Cu-PIII produces metallic copper inside the created titanium oxide compound. The length of the PIII pulses can exert control over the ion flux and the substrate temperature. H2O-Cu-PIII produces rutile structures with copper inside the lattice. The antimicrobial activity is tested with bacteria and the cytocompatibility with osteoblasts is investigated.
引用
收藏
页码:B511 / B518
页数:8
相关论文
共 25 条
[1]   Solutions of oxygen in metal titans [J].
Ehrlich, P .
ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 1941, 247 (1/2) :53-64
[2]   Antimicrobial titanium/silver PVD coatings on titanium [J].
Ewald, Andrea ;
Glueckermann, Susanne K. ;
Thull, Roger ;
Gbureck, Uwe .
BIOMEDICAL ENGINEERING ONLINE, 2006, 5 (1)
[3]  
FAIRLEY N, 2005, CASA COOK BOOK 1, P21
[4]   Antibacterial poly(D,L-lactic acid) coating of medical implants using a biodegradable drug delivery technology [J].
Gollwitzer, H ;
Ibrahim, K ;
Meyer, H ;
Mittelmeier, W ;
Busch, R ;
Stemberger, A .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2003, 51 (03) :585-591
[5]   A novel antibacterial titania coating:: Metal ion toxicity and in vitro surface colonization [J].
Heidenau, F ;
Mittelmeier, W ;
Detsch, R ;
Haenle, M ;
Stenzel, F ;
Ziegler, G ;
Gollwitzer, H .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2005, 16 (10) :883-888
[6]   Reduction of thin oxidized copper films using a hot-filament hydrogen radical source [J].
Kondoh, E. ;
Fukasawa, M. ;
Ojimi, T. .
JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A, 2007, 25 (03) :415-420
[7]   Improving the biocompatibility of medical implants with plasma immersion ion implantation [J].
Mändl, S ;
Rauschenbach, B .
SURFACE & COATINGS TECHNOLOGY, 2002, 156 (1-3) :276-283
[8]   Plasma immersion ion implantation.: New technology for homogeneous modification of the surface of medical implants of complex shapes [J].
Mändl, S ;
Rauschenbach, B .
BIOMEDIZINISCHE TECHNIK, 2000, 45 (7-8) :193-198
[9]   Plasma diagnostics for surface modification of polymers [J].
Meichsner, J ;
Zeuner, M ;
Krames, B ;
Nitschke, M ;
Rochotzki, R ;
Barucki, K .
SURFACE & COATINGS TECHNOLOGY, 1998, 98 (1-3) :1565-1571
[10]  
Moulder J.F., 1992, Handbook of X-ray Photoelectron Spectroscopy, P87