Short-lasting impairment of temperature perception by high frequency rTMS of the sensorimotor cortex

被引：21
作者：
Oliviero, A
Esteban, MR
de la Cruz, FS
Cabredo, LF
Di Lazzaro, V
机构：
[1] Hosp Nacl Paraplejicos, Unidad Neurol Func, SESCAM, Toledo 45071, Spain
[2] Hosp Nacl Paraplejicos, FENNSI Grp, Toledo 45071, Spain
[3] Univ Sacred Heart, Ist Neurol, I-00168 Rome, Italy
来源：
CLINICAL NEUROPHYSIOLOGY | 2005年 / 116卷 / 05期
关键词：
repetitive transcranial magnetic stimulation; quantitative sensory testing; temperature; motor cortex;
D O I：
10.1016/j.clinph.2004.12.003
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Objective: Repetitive transcranial magnetic stimulation (rTMS) has become a useful tool for investigating and even modulating human brain function. RTMS of the human motor cortex can produce changes in excitability that outlast the period of stimulation. To investigate the persistent effect of high-frequency rTMS of sensorimotor cortex (SM1) on somatosensory function. Methods: We evaluated the thermal thresholds (cold and warm sensation) in 14 normal subjects before and after a short train of 5 Hz rTMS over the SM1 or occipital cortex (OC). Results: Threshold for cold perception was increased immediately after rTMS of the left SM1 and no effects at all were noticed after OC stimulation. There was a slight, not significant, increase of warm threshold immediately after the rTMS of the left SM1 and no effects at all were noticed after OC stimulation. Conclusions: High frequency rTMS over primary sensorimotor cortex seems to modulate sensory function related to thermal (cold) perception. Significance: The method may be useful for both the study of normal human physiology of temperature perception and for rTMS based manipulation of brain plasticity in patients with sensory disturbances. (c) 2005 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：1072 / 1076
页数：5
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