Microwave-assisted one-pot synthesis of 2,4-disubstituted quinolines under solvent-free conditions

被引：47

作者：

Yadav, JS ^{[1
]}

Reddy, BVS ^{[1
]}

Rao, RS ^{[1
]}

Naveenkumar, V ^{[1
]}

Nagaiah, K ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

SYNTHESIS-STUTTGART | 2003年 / 10期

关键词：

microwave; aryl imines; alkynes; substituted quinolines;

D O I：

10.1055/s-2003-40531

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aromatic imines derived in situ from aryl aldehydes and aryl amines undergo smoothly, cyclization with alkynes on the surface of montmorillonite clay impregnated with copper(I) bromide under solvent-free conditions to produce 2,4-disubstituted quinolines in high yields with excellent selectivity. The reaction rates and yields are significantly improved by employing microwave irradiation.

引用

页码：1610 / 1614

页数：5

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