Nucleotide sequence homology to bovine viral diarrhea virus 2 (BVDV 2) in the 5′ untranslated region of BVDVs from cattle with mucosal disease or persistent infection in Japan

被引：59

作者：

Nagai, M

Sato, M

Nagano, H

Pang, H

Kong, X

Murakami, T

Ozawa, T

Akashi, H ^{[1
]}

机构：

[1] Nanbu Livestock Hyg Serv Ctr, Kanazawa, Ishikawa 9203101, Japan

[2] Utsunomiya Livestock Hyg Serv Ctr, Utsunomiya, Tochigi 3200072, Japan

[3] Gifu Livestock Hyg Serv Ctr, Gifu 5008388, Japan

[4] Natl Inst Anim Hlth, Tsukuba, Ibaraki 3050856, Japan

来源：

VETERINARY MICROBIOLOGY | 1998年 / 60卷 / 2-4期

关键词：

BVDV; 2; mucosal disease; new Japanese serotype; persistent infection; 5 ' UTR;

D O I：

10.1016/S0378-1135(98)00158-8

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Cytopathogenic and non-cytopathogenic bovine viral diarrhea viruses (BVDVs) were isolated from cattle with mucosal disease or persistent infection in Japan. These isolates were compared for antigenic properties by cross-neutralization tests with Japanese reference strains of BVDV belonging to classical type 1. Significantly low cross-reactivity to reference strains was noted, indicating the viruses to possibly represent a new serotype in Japan. Thus, to determine the genotype of the isolates, nucleotide sequences of the 5' untranslated region were determined and compared with those of previously reported BVDV 1 and 2. The isolates were clearly shown to belong to BVDV 2, not to BVDV 1. (C) 1998 Elsevier Science B.V.

引用

页码：271 / 276

页数：6

共 25 条

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