Anatomical and functional results of macular hole surgery with internal limiting membrane peeling after 10-year follow-up

Purpose. - To evaluate the anatomical and functional results of macular hole surgery with internal limiting membrane (ILM) peeling after 10 years follow-up. Methods. - Monocentric retrospective study of patients who had undergone macular hole surgery between 2003 and 2005 in the Nancy University Medical Center and still followed in the department in 2014. All patients underwent pars plana vitrectomy and ILM peeling without staining. Clinical examination at ten years including determination of best-corrected visual acuity (BCVA), evaluation of quality of life and spectral domain optical coherence tomography was performed. Results. - Four men and six women with mean age of 64 8 years were included. The mean diameter of the MH was 395 +/- 133 mu m. The mean best corrected visual acuity improved significantly from 0.90 +/- 0.22 logMAR to 0.14 +/- 0.14 logMAR after 10 years with a satisfactory quality of Life in 90 % of patients. The integrity of the IS/OS layer was preserved in 9 eyes. Inner retinal dimples Located in the temporal quadrant related to ILM peeling initiation were observed in 8 eyes. No significant RNFL or ganglion cell complex changes were found compared to the contralateral eye. Conclusion. - Macular hole surgery with ILM peeling in this series resulted in a visual acuity gain of 8 ETDRS tines and persistent improvement in quality of life after a 10-year follow-up. (C) 2016 Elsevier Masson SAS. All rights reserved.