Non-coding RNA in cancer

被引：392
|
作者：
Yan, Huiwen [1 ]
Bu, Pengcheng [1 ,2 ,3 ]
机构：
[1] Chinese Acad Sci, Inst Biophys, Key Lab RNA Biol, Key Lab Prot & Peptide Pharmaceut, Beijing 100101, Peoples R China
[2] Univ Chinese Acad Sci, Coll Life Sci, Beijing 100049, Peoples R China
[3] Chinese Acad Sci, Ctr Excellence Biomacromol, Beijing 100101, Peoples R China
来源：
NON-CODING GENOME | 2021年 / 65卷 / 04期
基金：
中国国家自然科学基金;
关键词：
PROMOTES CELL-PROLIFERATION; COLORECTAL-CANCER; BREAST-CANCER; HEPATOCELLULAR-CARCINOMA; PROSTATE-CANCER; CYCLE PROGRESSION; UP-REGULATION; LUNG-CANCER; STEM-CELLS; INVASION;
D O I：
10.1042/EBC20200032
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Majority of the human genome is transcribed to RNAs that do not encode proteins. These non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of various cancers. Given the importance of the ncRNAs, the roles of ncRNAs in cancers have been reviewed elsewhere. Thus, in this review, we mainly focus on the recent studies of the function, regulatory mechanism and therapeutic potential of the ncRNAs including microRNA (miRNA), long ncRNA (lncRNA), circular RNA (circRNA) and PIWI interacting RNA (piRNA), in different type of cancers.
引用
收藏
页码：625 / 639
页数：15
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