An efficient route to all eight stereoisomers of a tri-functionalised cyclopentane scaffold for drug discovery

被引：21

作者：

Smith, MEB ^{[1
]}

Lloyd, MC ^{[1
]}

Derrien, N ^{[1
]}

Lloyd, RC ^{[1
]}

Taylor, SJC ^{[1
]}

Chaplin, DA ^{[1
]}

Casy, G ^{[1
]}

McCague, R ^{[1
]}

机构：

[1] Ascot Fine Chem, ChiroTech, Cambridge CB4 0WG, England

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 05期

关键词：

D O I：

10.1016/S0957-4166(01)00108-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A route to all eight stereoisomers of 3-(tert-butoxycarbonylamino)-4-hydroxycyclopentanecarboxylic acid methyl ester is presented; these products should prove to be valuable scaffolds in pharmaceutical discovery. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：703 / 705

页数：3

共 7 条

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