Mechanical design of an intracranial stent for treating cerebral aneurysms

被引:22
作者
Shobayashi, Yasuhiro [1 ,3 ]
Tanoue, Tetsuya [3 ]
Tateshima, Satoshi [2 ]
Tanishita, Kazuo [1 ]
机构
[1] Keio Univ, Dept Syst Design Engn, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan
[2] Univ Calif Los Angeles, David Geffen Sch Med, Div Intervent Neuroradiol, Los Angeles, CA 90095 USA
[3] Keio Univ, Grad Sch, Sch Integrated Design Engn, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan
关键词
Cerebral aneurysm; Endovascular treatment; Stent; Flexibility; Mechanical estimation; NATURAL-HISTORY; FOLLOW-UP; RISK; HEMODYNAMICS; EXPERIENCE; PLACEMENT; RUPTURE; MODELS;
D O I
10.1016/j.medengphy.2010.07.002
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Endovascular treatment of cerebral aneurysms using stents has advanced markedly in recent years Mechanically a cerebrovascular stent must be very flexible longitudinally and have low radial stiffness However no study has examined the stress distribution and deformation of cerebrovascular stents using the finite element method (FEM) and experiments Stents can have open- and closed-cell structures and open-cell stents are used clinically in the cerebrovasculature because of their high flexibility However the open-cell structure confers a risk of in-stent stenosis due to protrusion of stent struts into the normal parent artery Therefore a flexible stent with a closed-cell structure is required To design a clinically useful highly flexible closed-cell stent one must examine the mechanical properties of the closed-cell structure In this study we investigated the relationship between mesh patterns and the mechanical properties of closed-cell stents Several mesh patterns were designed and their characteristics were studied using numerical simulation The results showed that the bending stiffness of a closed-cell stent depends on the geometric configuration of the stent cell It decreases when the stent cell is stretched in the circumferential direction Mechanical flexibility equal to an open-cell structure was obtained in a closed-cell structure by varying the geometric configuration of the stent cell (C) 2010 IPEM Published by Elsevier Ltd All rights reserved
引用
收藏
页码:1015 / 1024
页数:10
相关论文
共 31 条
  • [1] Cyclic GMP-dependent protein kinase expression in coronary arterial smooth muscle in response to balloon catheter injury
    Anderson, PG
    Boerth, NJ
    Liu, M
    McNamara, DB
    Cornwell, TL
    Lincoln, TM
    [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2000, 20 (10) : 2192 - 2197
  • [2] ASHER LT, 2009, J BIOMECH ENG, V131
  • [3] Cebral JR, 2005, AM J NEURORADIOL, V26, P2550
  • [4] Physical properties of endovascular stents: An experimental comparison
    Duda, SH
    Wiskirchen, J
    Tepe, G
    Bitzer, M
    Kaulich, TW
    Stoeckel, D
    Claussen, CD
    [J]. JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2000, 11 (05) : 645 - 654
  • [5] Ebrahimi N, 2007, AM J NEURORADIOL, V28, P823
  • [6] Usefulness of the neuroform stent for the treatment of cerebral aneurysms: Results at initial (3-6-mo) follow-up
    Fiorella, D
    Albuquerque, FC
    Deshmukh, VR
    McDougall, CG
    [J]. NEUROSURGERY, 2005, 56 (06) : 1191 - 1201
  • [7] Gong P., 2002, P IMECE 2002, V53, P1
  • [8] Higashida RT, 2005, AM J NEURORADIOL, V26, P1751
  • [9] INOUE K, 2007, JPN SOC DES ENG, V42, P27
  • [10] *JAP SOC SPRING EN, 2008, SPRING MAR, P181