Long-term use of acid suppression started inappropriately during hospitalization

被引:117
作者
Zink, DA
Pohlman, M
Barnes, M
Cannon, ME
机构
[1] William Beaumont Hosp, Div Gastroenterol & Hepatol, Royal Oak, MI 48073 USA
[2] Univ Chicago, Div Pulm & Crit Care Med, Chicago, IL 60637 USA
[3] William Beaumont Hosp, Dept Internal Med, Royal Oak, MI 48073 USA
关键词
D O I
10.1111/j.1365-2036.2005.02454.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background: Practitioners routinely misuse acid suppression medications on general medical floors and inappropriately continue the drug at discharge. Aims: To: (i) retrospectively study the appropriateness of acid suppression use on the general medical floors; (ii) characterize the patient population discharged on unnecessary acid suppression and (iii) evaluate whether patients discharged on unnecessary acid suppression continue the medicine long term. Methods: Retrospective chart review of general medical patients admitted to an in-patient teaching service over 6 consecutive months. Results: About 60% of patients lacked an indication for initiation of acid suppression and 34% of these patients were discharged on the medicine. The only independent predictor of continuation of acid suppression at discharge was longer length of stay. Multivariate analysis did not identify a characteristic distinguishing those patients discharged inappropriately on acid suppression. At 3 and 6 months of follow-up, 80% and 50% of patients, respectively, remained on acid suppression therapy without an appropriate indication. Conclusions: Our data verifies that practitioners routinely start general medical in-patients on acid suppression without an appropriate indication. Many of these prescriptions are continued at discharge for no apparent reason, leading to their long-term misuse.
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页码:1203 / 1209
页数:7
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共 28 条
[1]  
BROE PJ, 1982, SURG GYNECOL OBSTET, V154, P13
[2]   CORTICOSTEROIDS AND PEPTIC-ULCER - METAANALYSIS OF ADVERSE EVENTS DURING STEROID-THERAPY [J].
CONN, HO ;
POYNARD, T .
JOURNAL OF INTERNAL MEDICINE, 1994, 236 (06) :619-632
[3]   RISK-FACTORS FOR GASTROINTESTINAL-BLEEDING IN CRITICALLY ILL PATIENTS [J].
COOK, DJ ;
FULLER, HD ;
GUYATT, GH ;
MARSHALL, JC ;
LEASA, D ;
HALL, R ;
WINTON, TL ;
RUTLEDGE, F ;
TODD, TJR ;
ROY, P ;
LACROIX, J ;
GRIFFITH, L ;
WILLAN, A ;
NOSEWORTHY, T ;
POWLES, P ;
OPPENHEIMER, L ;
HEWSON, J ;
LANG, J ;
LEE, H ;
GUSLITS, B ;
HEULE, M .
NEW ENGLAND JOURNAL OF MEDICINE, 1994, 330 (06) :377-381
[4]  
*CTR MED MED SERV, 2005, NAT HLTH DOLL 2003
[5]   Proton pump inhibitors as a risk factor for Clostridium difficile diarrhoea [J].
Cunningham, R ;
Dale, B ;
Undy, B ;
Gaunt, N .
JOURNAL OF HOSPITAL INFECTION, 2003, 54 (03) :243-245
[6]  
Erstad BL, 1999, AM J HEALTH-SYST PH, V56, P347
[7]   OMEPRAZOLE, HYPERGASTRINEMIA, AND GASTRIC CARCINOID-TUMORS [J].
FRESTON, JW .
ANNALS OF INTERNAL MEDICINE, 1994, 121 (03) :232-233
[8]   RISK FOR SERIOUS GASTROINTESTINAL COMPLICATIONS RELATED TO USE OF NONSTEROIDAL ANTIINFLAMMATORY DRUGS - A METAANALYSIS [J].
GABRIEL, SE ;
JAAKKIMAINEN, L ;
BOMBARDIER, C .
ANNALS OF INTERNAL MEDICINE, 1991, 115 (10) :787-796
[9]   A RANDOMIZED TRIAL COMPARING CIMETIDINE TO NASOGASTRIC SUCTION IN ACUTE-PANCREATITIS [J].
GOFF, JS ;
FEINBERG, LE ;
BRUGGE, WR .
DIGESTIVE DISEASES AND SCIENCES, 1982, 27 (12) :1085-1088
[10]   NONSTEROIDAL ANTIINFLAMMATORY DRUG-USE AND INCREASED RISK FOR PEPTIC-ULCER DISEASE IN ELDERLY PERSONS [J].
GRIFFIN, MR ;
PIPER, JM ;
DAUGHERTY, JR ;
SNOWDEN, M ;
RAY, WA .
ANNALS OF INTERNAL MEDICINE, 1991, 114 (04) :257-263