Enantioselective 1,3-dipolar cycloaddition reactions between nitrones and α-substituted α,β-unsaturated aldehydes catalyzed by chiral cationic cobalt(III) complexes

被引：0

作者：

Ohtsuki, N ^{[1
]}

Kezuka, S ^{[1
]}

Kogami, Y ^{[1
]}

Mita, T ^{[1
]}

Ashizawa, T ^{[1
]}

Ikeno, T ^{[1
]}

Yamada, T ^{[1
]}

机构：

[1] Keio Univ, Fac Sci & Technol, Dept Chem, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan

来源：

SYNTHESIS-STUTTGART | 2003年 / 09期

关键词：

aldehyde; asymmetric catalysis; complexes; cycloadditions; nitrones;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The optically active beta-ketoiminato cationic cobalt(III) complexes catalyzed the 1,3-dipolar cycloaddition reaction of nitrones with alpha,beta-unsaturated aldehydes. In the reaction of nitrones derived from 2-halobenzaldehyde, excellent endo-selectivities and high enantioselectivities were observed. The alpha-substituted alpha,beta-unsaturated aldehyde, such as 2-benzylpropenal, afforded the corresponding isoxazolidine in high stereoselectivity.

引用

页码：1462 / 1466

页数：5

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