Clinical Translation of Three-Dimensional Scar, Diffusion Tensor Imaging, Four-Dimensional Flow, and Quantitative Perfusion in Cardiac MRI: A Comprehensive Review

被引：15

作者：

Paddock, Sophie ^{[1
,2
]}

Tsampasian, Vasiliki ^{[1
]}

Assadi, Hosamadin ^{[3
]}

Mota, Bruno Calife ^{[2
]}

Swift, Andrew J. ^{[3
]}

Chowdhary, Amrit ^{[4
]}

Swoboda, Peter ^{[4
]}

Levelt, Eylem ^{[4
]}

Sammut, Eva ^{[5
,6
]}

Dastidar, Amardeep ^{[5
,6
]}

Cabrero, Jordi Broncano ^{[7
]}

Del Val, Javier Royuela ^{[7
]}

Malcolm, Paul ^{[1
]}

Sun, Julia ^{[2
]}

Ryding, Alisdair ^{[2
]}

Sawh, Chris ^{[2
]}

Greenwood, Richard ^{[2
]}

Hewson, David ^{[2
]}

Vassiliou, Vassilios ^{[1
]}

Garg, Pankaj ^{[1
,3
]}

机构：

[1] Univ East Anglia, Norwich Med Sch, Dept Cardiovasc & Metab Hlth, Norwich, Norfolk, England

[2] Norfolk & Norwich Univ Hosp, Dept Cardiol, Norwich, Norfolk, England

[3] Univ Sheffield, Dept Infect Immun & Cardiovasc Dis, Sheffield, S Yorkshire, England

[4] Univ Leeds, Multidisciplinary Cardiovasc Res Ctr, Leeds Inst Cardiovasc & Metab Med, Leeds, W Yorkshire, England

[5] Univ Bristol, Fac Hlth Sci, Bristol Heart Inst, Bristol, Avon, England

[6] Univ Bristol, Fac Hlth Sci, Translat Biomed Res Ctr, Bristol, Avon, England

[7] Hosp San Juan Dios, Cardiothorac Imaging Unit, HT Med, Cordoba, Spain

来源：

FRONTIERS IN CARDIOVASCULAR MEDICINE | 2021年 / 8卷

基金：

英国惠康基金;

关键词：

cardiovascular magnetic resonance; diffusion tensor imaging; tissue characterisation; myocardial fibrosis; four-dimensional flow imaging; CORONARY-ARTERY-DISEASE; CARDIOVASCULAR MAGNETIC-RESONANCE; EMISSION COMPUTED-TOMOGRAPHY; MYOCARDIAL BLOOD-FLOW; LATE GADOLINIUM ENHANCEMENT; IN-VIVO; FIBER ARCHITECTURE; EXTRACTION EFFICIENCY; PROGNOSTIC VALUE; GD-DTPA;

D O I：

10.3389/fcvm.2021.682027

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cardiovascular magnetic resonance (CMR) imaging is a versatile tool that has established itself as the reference method for functional assessment and tissue characterisation. CMR helps to diagnose, monitor disease course and sub-phenotype disease states. Several emerging CMR methods have the potential to offer a personalised medicine approach to treatment. CMR tissue characterisation is used to assess myocardial oedema, inflammation or thrombus in various disease conditions. CMR derived scar maps have the potential to inform ablation therapy-both in atrial and ventricular arrhythmias. Quantitative CMR is pushing boundaries with motion corrections in tissue characterisation and first-pass perfusion. Advanced tissue characterisation by imaging the myocardial fibre orientation using diffusion tensor imaging (DTI), has also demonstrated novel insights in patients with cardiomyopathies. Enhanced flow assessment using four-dimensional flow (4D flow) CMR, where time is the fourth dimension, allows quantification of transvalvular flow to a high degree of accuracy for all four-valves within the same cardiac cycle. This review discusses these emerging methods and others in detail and gives the reader a foresight of how CMR will evolve into a powerful clinical tool in offering a precision medicine approach to treatment, diagnosis, and detection of disease.

引用

页数：16

共 146 条

[71] In-Scan and Scan-Rescan Assessment of LV In- and Outflow Volumes by 4D Flow MRI Versus 2D Planimetry [J].