How does the convergence of prematurity and congenital heart disease impact the developing brain?

被引：4

作者：

Gano, Dawn ^{[1
,2
]}

McQuillen, Patrick ^{[2
]}

机构：

[1] Univ Calif San Francisco, Dept Neurol, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Dept Pediat, San Francisco, CA 94143 USA

来源：

SEMINARS IN PERINATOLOGY | 2021年 / 45卷 / 07期

基金：

美国国家卫生研究院;

关键词：

Preterm; Congenital heart defects; Brain injury; Magnetic resonance imaging; WHITE-MATTER INJURY; NEURODEVELOPMENTAL OUTCOMES; CEREBELLAR INJURY; INTRAVENTRICULAR HEMORRHAGE; CARDIAC-SURGERY; INFANTS; NEWBORNS; GROWTH; MICROSTRUCTURE; RISK;

D O I：

10.1016/j.semperi.2021.151472

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Prematurity and congenital heart disease (CHD) are individually associated with increased risk of brain injury and adverse neurodevelopmental outcomes. Delayed brain development in newborns with CHD has been documented to begin in utero and predisposes newborns with CHD to brain injury. Little is known about the combined risks when prematurity and CHD co-occur. The purpose of this review is to highlight the unique vulnerability of preterm newborns with CHD to brain dysmaturation and brain injury, and the urgent need for prospective research. (c) 2021 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

引用

页数：7

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