Microwave-assisted synthesis of quinazolin-4(3H)-ones catalyzed by SbCl3

被引：8

作者：

Kang, Huaiyuan ^{[1
]}

Wang, Weili ^{[1
]}

Sun, Qinqiang ^{[1
]}

Yang, Shuya ^{[1
]}

Jin, Juan ^{[1
,2
]}

Zhang, Xuewen ^{[1
]}

Ren, Xiaoliang ^{[2
]}

Zhang, Jiming ^{[2
]}

Zhou, Jianhua ^{[2
]}

机构：

[1] Ludong Univ, Sch Chem & Mat Sci, Yantai 264025, Peoples R China

[2] Qilu Univ Technol, Sch Chem & Pharmaceut Engn, Jinan 250353, Shandong, Peoples R China

来源：

HETEROCYCLIC COMMUNICATIONS | 2018年 / 24卷 / 06期

关键词：

microwave irradiation; quinazolin-4(3H)-ones; SbCl3; solvent-free; ONE-POT SYNTHESIS; SOLVENT-FREE SYNTHESIS; FREE FATTY-ACID; EFFICIENT SYNTHESIS; CASCADE SYNTHESIS; QUINAZOLINONES; ESTERIFICATION; DERIVATIVES; ALDEHYDES; CHLORIDE;

D O I：

10.1515/hc-2018-0115

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Antimony(III) trichloride (SbCl3) is an effective catalyst (1 mol%) for the condensation of anthranilic amide with various aldehydes or ketones to quinazolin-4(3H)-one derivatives in good to excellent yields under microwave irradiation. The process is carried out within several minutes under solvent-free conditions. This general methodology has the advantages of simplicity, mild reaction conditions and high yields of products.

引用

页码：293 / 296

页数：4

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