Immunity against cancer: lessons learned from melanoma

被引：157

作者：

Houghton, AN

Gold, JS

Blachere, NE

机构：

[1] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA

[2] Cornell Univ, Weill Med Sch, New York, NY 10021 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2001年 / 13卷 / 02期

关键词：

D O I：

10.1016/S0952-7915(00)00195-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Most major advances in human cancer immunology and immunotherapy have come from studies in melanoma. We are beginning to understand the immune repertoire of T cells and antibodies that are active against melanoma, with recent glimpses of the CD4(+) T cell repertoire. The view of what the immune system can see is extending to mutations and parts of the genome that are normally invisible.

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页码：134 / 140

页数：7

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