Nickel-catalyzed highly regio- and stereoselective cyclization of oxanorbornenes with alkyl propiolates: A novel method for the synthesis of benzocoumarin derivatives

被引：0

作者：

Rayabarapu, DK ^{[1
]}

Sambaiah, T ^{[1
]}

Cheng, CH ^{[1
]}

机构：

[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu 300, Taiwan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2001年 / 40卷 / 07期

关键词：

alkenes; coumarins; cyclization; nickel;

D O I：

10.1002/1521-3773(20010401)40:7<1286::AID-ANIE1286>3.0.CO;2-I

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

7-Oxabenzonorbornadienes bearing various substituents react with propiolates in the presence of [NiBr2(dppe)] (dppe = bis(diphenylphosphanyl)ethane) as a catalyst precursor and zinc powder to give benzocoumarin derivatives [Eq. (1)]. The one-pot reactions proceed at 80°C in acetonitrile, and the products are obtained in good yields with high regio- and stereoselectivity.

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页码：1286 / +

页数：4

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