Synthesis of 2-substituted 3,4-bis(diethoxyphosphorylmethyl)furans

被引：6
作者：
Pevzner, L. M. [1 ]
机构：
[1] Tech Univ, St Petersburg State Technol Inst, St Petersburg 190031, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2015年 / 85卷 / 02期
关键词：
diphosphonate; synthesis; 2,4,5-substituted furan; furancarboxylic acid derivative; BISPHOSPHONATES; ACID;
D O I：
10.1134/S1070363215020139
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Bromination of ethyl 4-(diethoxyphosphorylmethyl)-5-methylfuran-2-carboxylate and 4-(diethoxyphosphorylmethyl)-5-methylfuran-2-carbonitrile with N-bromosuccinimide followed by phosphorylation via the Arbuzov reaction have yielded the corresponding 2-substituted 4,5-bis(diethoxyphosphorylmethyl)furans. Synthesis and transformations of bisphosphorylated 2-furoic acid and its derivatives are described.
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收藏
页码：428 / 435
页数：8
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